ReviewNutrients2014
Obesity as an emerging risk factor for iron deficiency.
Review in Nutrients, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 152 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
152 citing papers in PubMed, 2 syntheses or guidelines pooled it, 309 citations in OpenAlex.
- Iron overload disorders in adults: a comprehensive review of gonadal function, reproductive, and sexual health.Human reproduction update · 2026Pooled it
- Pooled it
- Effect of Epigallocatechin Gallate Supplementation on Inflammation, Iron Status, and Metabolomic Profiles in Women With Obesity: A Pilot Randomized Controlled Trial.Molecular nutrition & food research · 2026Trial
- Effect of green-lipped mussel (Journal of nutritional science · 2023Trial
- Overweight and obesity among urban women with iron deficiency anaemia in Bangladesh.Maternal & child nutrition · 2021Trial
- Screening umbilical cord blood for congenital Iron deficiency.Blood cells, molecules & diseases · 2019Trial
- Influence of endurance and endurance-strength training on mineral status in women with abdominal obesity: a randomized trial.Medicine · 2019Trial
- Acupuncture Improves Intestinal Absorption of Iron in Iron-deficient Obese Patients: A Randomized Controlled Preliminary Trial.Chinese medical journal · 2017Trial
- Obesity and Iron Metabolism: Mechanisms, Status Assessment, and Clinical Implications.Current obesity reports · 2026Review
- Iron Deficiency in Endocrine Diseases and the Therapeutic Role of Liposomal Iron: A Comprehensive Review.Biomedicines · 2026Review
- Article
- Observational
- Review
- Associations of Serum Zinc and Iron with Systemic Inflammatory Indices in Pediatric Obesity: An Exploratory Cross-Sectional Study.Children (Basel, Switzerland) · 2026Article
- Article
- Pediatric Oral Iron Therapy: Choosing the Right Product for Your Patient.Hematology reports · 2026Review
- Dietary Iron Intake and Risk of Gastric Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- Association between leptin gene polymorphisms and hematological metabolic parameters in obese Saudi adults.Frontiers in medicine · 2026Article
- Underweight Status is Associated with Prevalent Anemia in Postmenopausal Women with Osteoporotic Vertebral Compression Fractures: A Cross-Sectional Study.Clinical interventions in aging · 2026Article
- Article
92 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iron homeostasis is affected by obesity and obesity-related insulin resistance in a many-facetted fashion. On one hand, iron deficiency and anemia are frequent findings in subjects with progressed stages of obesity. This phenomenon has been well studied in obese adolescents, women and subjects undergoing bariatric surgery. On the other hand, hyperferritinemia with normal or mildly elevated transferrin saturation is observed in approximately one-third of patients with metabolic syndrome (MetS) or nonalcoholic fatty liver disease (NAFLD). This constellation has been named the "dysmetabolic iron overload syndrome (DIOS)". Both elevated body iron stores and iron deficiency are detrimental to health and to the course of obesity-related conditions. Iron deficiency and anemia may impair mitochondrial and cellular energy homeostasis and further increase inactivity and fatigue of obese subjects. Obesity-associated inflammation is tightly linked to iron deficiency and involves impaired duodenal iron absorption associated with low expression of duodenal ferroportin (FPN) along with elevated hepcidin concentrations. This review summarizes the current understanding of the dysregulation of iron homeostasis in obesity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.