Evidence map›Paper›PMID 25215309›Full record

ArticleInternational trends in immunity2014

Anti-HSV activity of serpin antithrombin III.

Debra C Quenelle, Tracy L Hartman, Robert W Buckheit, Mark N Prichard, Ralf Geiben Lynn

Open access · greenAbstract read
In one paragraph

Article in International trends in immunity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Antithrombin and Its Role in Host Defense and Inflammation.International journal of molecular sciences · 2021
    Review
  2. Article
  3. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Debra C QuenelleDepartment of Pediatrics, University of Alabama at Birmingham, USA.
Tracy L HartmanImquest BioSciences, Inc., Frederick, Maryland, USA.
Robert W BuckheitImquest BioSciences, Inc., Frederick, Maryland, USA.
Mark N PrichardDepartment of Pediatrics, University of Alabama at Birmingham, USA.
Ralf Geiben LynnAcceleration BioPharmaceuticals, Inc. Woburn, MA, USA.
University of Alabama at Birmingham · US

Funding

NIAID NIH HHS HHSN272201000027CNIAID NIH HHS N01 AI030049
6 · The paper itself

Abstract

Natural serine protease inhibitors (serpins) elicit sensing of a microbial cell intruder and activate an intrinsic cellular immune response in HIV and HCV infected cells. Here, we demonstrate

Indexed as

acyclovir-resistant HSV-1Antithrombin IIIHSVmice abrasion modelserine protease inhibitorserpin

Identifiers

PMID25215309
PMCPMC4158439
OpenAlexW2289481766

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.