ArticleDiabetes & metabolism journal2014
The Effects of Propofol and Isoflurane on Blood Glucose during Abdominal Hysterectomy in Diabetic Patients.
Article in Diabetes & metabolism journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Effects of Intravenous or Inhalation Anesthesia on Blood Glucose in Patients with Type 2 Diabetes Mellitus: A PRISMA-Compliant Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Trial
- Hypoglycaemia in a patient with undiagnosed Doege-Potter syndrome: A case report and narrative literature review.European journal of anaesthesiology and intensive care · 2026Review
- Stable intracranial imaging of dura mater-engrafted pancreatic islet cells in awake mice.Nature communications · 2025Article
- Bidirectional Relationship Between Anaesthetic Drugs and Metabolic Syndrome: Clinical Effects and Mechanisms.Journal of cellular and molecular medicine · 2025Review
- The Perioperative Neonatal and Maternal Glycemic Response and APGAR Score During Elective Cesarean Section: Factors and Anesthetic Management.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2025Article
- Comparison of spinal versus general anesthesia on the perioperative blood glucose levels in patients undergoing lower abdominal and pelvic surgery: a prospective cohort study, Ethiopia.Annals of medicine and surgery (2012) · 2023Article
- Ketone supplementation abolished isoflurane anesthesia-induced elevation in blood glucose level and increased recovery time from anesthesia in Wistar Albino Glaxo Rijswijk rats.BMC anesthesiology · 2023Article
- Feasibility of Interstitial Fluid Ketone Monitoring with Microneedles.Metabolites · 2022Article
- Use of a bio-electronic device comprising of targeted dual neuromodulation of the hepatic and celiac vagal branches demonstrated enhanced glycemic control in a type 2 diabetic rat model as well as in an Alloxan treated swine model.Frontiers in neuroscience · 2022Article
- The influence of anesthesia type on perioperative maternal glycemic-stress response during elective cesarean section: A prospective cohort study.Annals of medicine and surgery (2012) · 2021Article
- Amelioration of Hippocampal Insulin Resistance Reduces Tau Hyperphosphorylation and Cognitive Decline Induced by Isoflurane in Mice.Frontiers in aging neuroscience · 2021Article
- Isoflurane and Carbon Dioxide Elicit Similar Behavioral Responses in Rats.Animals : an open access journal from MDPI · 2020Article
- Propofol Improved Glucose Tolerance Associated with Increased FGF-21 and GLP-1 Production in Male Sprague-Dawley Rats.Molecules (Basel, Switzerland) · 2020Article
- Dexmedetomidine alleviates insulin resistance in hepatocytes by reducing endoplasmic reticulum stress.Endocrine · 2020Article
- Effect of Spinal Anesthesia versus General Anesthesia on Blood Glucose Concentration in Patients Undergoing Elective Cesarean Section Surgery: A Prospective Comparative Study.Anesthesiology research and practice · 2019Article
- Comparison of sevoflurane and propofol anesthesia on the incidence of hyperglycemia in patients with type 2 diabetes undergoing lung surgery.Yeungnam University journal of medicine · 2018Article
- Biomimetic electrospun coatings increase the in vivo sensitivity of implantable glucose biosensors.Journal of biomedical materials research. Part A · 2018Article
- Metabolic response to three different diets in lean cats and cats predisposed to overweight.BMC veterinary research · 2017Article
- Isoflurane and Sevoflurane Induce Severe Hepatic Insulin Resistance in a Canine Model.PloS one · 2016Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute hyperglycemia in the perioperative period is associated with significantly increased complications. In few human studies the effects of propofol and inhalational anesthetic on the glucose metabolism were compared. In this study we evaluated the effect of propofol and isoflurane on blood glucose during abdominal hysterectomy in diabetic patients.
methodsAfter approval by the Ethical Committee and written informed consent, thirty 35 to 65 years old diabetic women underwent for elective abdominal hysterectomy under general anesthesia were studied in this randomized single blind clinical trial study. The plasma glucose was maintained at 100 to 180 mg/dL during the operation. Anesthesia protocol was similar in two groups except maintenance of anesthesia that was with infusion of propofol in the propofol group and with isoflurane in the isoflurane group. Blood glucose level and the rate of insulin intake during surgery compared between two groups.
resultsMean blood glucose before induction of anesthesia did not have significant difference between two groups, but 60 and 90 minutes after starting the operation blood glucose in the propofol group was significantly lower than isoflurane group. Also with using Repeated Measure test, two groups was significantly different according to blood glucose (P=0.045). Mean of administration of insulin during the surgery did not have significant difference between two groups by using repeated measure test and P=0.271. Also mean of bispectral index in different times during the surgery between two groups didn't have significant difference (P=0.35 repeated measure test).
conclusionBlood glucose increased during maintenance of anesthesia with isoflurane compared to propofol during the surgery.
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