Evidence map›Paper›PMID 25215268›Full record

ArticleCurrent opinion in chemical engineering2014

Solution of Chemical Master Equations for Nonlinear Stochastic Reaction Networks.

Patrick Smadbeck, Yiannis N Kaznessis

Abstract read
In one paragraph

Article in Current opinion in chemical engineering, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Patrick SmadbeckDepartment of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455, USA.
Yiannis N KaznessisDepartment of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455, USA.

Funding

Multiscale Models for Synthetic BiologyR01GM086865 · NIGMS · UNIVERSITY OF MINNESOTA · PI KAZNESSIS, YIANNIS · 2009 to 2010
$497k
NIGMS NIH HHS R01 GM086865
6 · The paper itself

Abstract

Stochasticity in the dynamics of small reacting systems requires discrete-probabilistic models of reaction kinetics instead of traditional continuous-deterministic ones. The master probability equation is a complete model of randomly evolving molecular populations. Because of its ambitious character, the master equation remained unsolved for all but the simplest of molecular interaction networks. With the first solution of chemical master equations, a wide range of experimental observations of small-system interactions may be mathematically conceptualized.

Indexed as

Chemical Master EquationClosure SchemeStochastic Reaction Networks

Identifiers

PMID25215268
PMCPMC4157358

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.