ArticleCurrent otorhinolaryngology reports2014
Intratympanic Therapies for Menière's disease.
Article in Current otorhinolaryngology reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Use of Skull Vibration-Induced Nystagmus in the Follow-up of Patients With Ménière Disease Treated With Intratympanic Gentamicin.Clinical and experimental otorhinolaryngology · 2023Article
- Radiologic anatomy of the round window relevant to cochlear implantation and inner ear drug delivery.World journal of otorhinolaryngology - head and neck surgery · 2021Article
- Genetics and the Individualized Therapy of Vestibular Disorders.Frontiers in neurology · 2021Review
- Intratympanic gentamycine for Ménière's disease: is there a selective vestibulotoxic effect?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Article
- New marsupialization technique in endolymphatic sac surgery.Laryngoscope investigative otolaryngology · 2020Article
- Comparison of Enhancement of the Vestibular Perilymph between Variable and Constant Flip Angle-Delayed 3D-FLAIR Sequences in Menière Disease.AJNR. American journal of neuroradiology · 2020Article
- Effects of an Intratympanic Injection of Dexamethasone Combined with Gentamicin on the Expression Level of Serum P0 Protein Antibodies in Patients with Meniere's Disease.Clinics (Sao Paulo, Brazil) · 2020Article
- In vivo imaging of saccular hydrops in humans reflects sensorineural hearing loss rather than Meniere's disease symptoms.European radiology · 2018Article
- Methylprednisolone versus Dexamethasone for Control of Vertigo in Patients with Definite Meniere's disease.Iranian journal of otorhinolaryngology · 2017Article
- Intratympanic corticosteroids in Ménière's disease: A mini-review.Journal of otology · 2017Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
There are multiple treatment options to consider when managing patients with Menière's disease. When conservative measures fail to control symptoms of Menière's disease, escalation of interventions may be required. Targeted drug delivery to the round window with intratympanic injections allows for local application of high concentrations of medications, largely avoiding systemic side effects. Intratympanic steroids have been shown to be effective at controlling vertigo symptoms, with less robust control rates than those seen with the use of intratympanic gentamicin. Dosing strategies have been modified over time to limit the potential for intratympanic gentamicin-induced ototoxicity. The introduction of intratympanic steroids coupled to a polymer designed for sustained round window drug application, may potentially afford improved duration of symptom control. This review evaluates the recent literature over the last year involving intratympanic therapies for Meniere's disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.