Evidence map›Paper›PMID 25215101›Full record

ArticleWorld journal of emergency medicine2013

Evaluating the management of anaphylaxis in US emergency departments: Guidelines vs. practice.

W Scott Russell, Judith Rosen Farrar, Richard Nowak, Daniel P Hays, Natalie Schmitz, Joseph Wood, Judi Miller

Abstract read
In one paragraph

Article in World journal of emergency medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. How to define severity: A review of allergic reaction severity scoring systems.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Drug-induced anaphylaxis in the emergency room.Acute medicine & surgery · 2017
    Review
  14. Anaphylaxis in America: A national physician survey.The Journal of allergy and clinical immunology · 2015
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

W Scott RussellPediatric Emergency Department, Medical University of South Carolina, Charleston, SC 29425, USA.
Judith Rosen FarrarLife Sciences Press, Canandaigua, NY, USA.
Richard NowakDepartment of Emergency Medicine, Henry Ford Health System, Detroit, MI, USA.
Daniel P HaysUniversity of Arizona Medical Center, Tucson, AZ, USA.
Natalie SchmitzDeKalb Medical Center, Atlanta, GA, USA.
Joseph WoodMayo Clinic Arizona, Scottsdale, AZ, USA.
Judi MillerSRxA, Washington, DC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnaphylaxis is characterized by acute episodes of potentially life-threatening symptoms that are often treated in the emergency setting. Current guidelines recommend: 1) quick diagnosis using standard criteria; 2) first-line treatment with epinephrine; and 3) discharge with a prescription for an epinephrine auto-injector, written instructions regarding long-term management, and a referral (preferably, allergy) for follow-up. However, studies suggest low concordance with guideline recommendations by emergency medicine (EM) providers. The study aimed to evaluate how emergency departments (EDs) in the United States (US) manage anaphylaxis in relation to guideline recommendations.

methodsThis was an online anonymous survey of a random sample of EM health providers in US EDs.

resultsData analysis included 207 EM providers. For respondent EDs, approximately 9% reported using agreed-upon clinical criteria to diagnose anaphylaxis; 42% reported administering epinephrine in the ED for most anaphylaxis episodes; and <50% provided patients with a prescription for an epinephrine auto-injector and/or an allergist referral on discharge. Most provided some written materials, and follow-up with a primary care clinician was recommended.

conclusionsThis is the first cross-sectional survey to provide "real-world" data showing that practice in US EDs is discordant with current guideline recommendations for the diagnosis, treatment, and follow-up of patients with anaphylaxis. The primary gaps are low (or no) utilization of standard criteria for defining anaphylaxis and inconsistent use of epinephrine. Prospective research is recommended.

Indexed as

Allergic reactionAnaphylaxisEmergency departmentEpinephrine (adrenaline)Epinephrine autoinjectorGuidelinesLife-threatening reactionSelf-injectable epinephrine

Identifiers

PMID25215101
PMCPMC4129832

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.