Evidence map›Paper›PMID 25214883›Full record

ReviewComputational and mathematical methods in medicine2014

Biomedical relation extraction: from binary to complex.

Deyu Zhou, Dayou Zhong, Yulan He

Open access · hybridAbstract readReview
In one paragraph

Review in Computational and mathematical methods in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 93 citations in OpenAlex.

  1. The Role of N-ary Relations in Representing Biomedical Complexity.Methods in molecular biology (Clifton, N.J.) · 2026
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  8. A Study of Biomedical Relation Extraction Using GPT Models.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024
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  14. Chemical-protein relation extraction with ensembles of carefully tuned pretrained language models.Database : the journal of biological databases and curation · 2022
    Article
  15. BertSRC: transformer-based semantic relation classification.BMC medical informatics and decision making · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Deyu ZhouSchool of Computer Science and Engineering, Key Laboratory of Computer Network and Information Integration, Ministry of Education, Southeast University, Nanjing 210096, China.ORCID 0000-0001-7702-9387
Dayou ZhongSchool of Computer Science and Engineering, Key Laboratory of Computer Network and Information Integration, Ministry of Education, Southeast University, Nanjing 210096, China.
Yulan HeSchool of Engineering and Applied Science, Aston University, Birmingham B4 7ET, UK.ORCID 0000-0003-3948-5845
Southeast University · CNAston University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomedical relation extraction aims to uncover high-quality relations from life science literature with high accuracy and efficiency. Early biomedical relation extraction tasks focused on capturing binary relations, such as protein-protein interactions, which are crucial for virtually every process in a living cell. Information about these interactions provides the foundations for new therapeutic approaches. In recent years, more interests have been shifted to the extraction of complex relations such as biomolecular events. While complex relations go beyond binary relations and involve more than two arguments, they might also take another relation as an argument. In the paper, we conduct a thorough survey on the research in biomedical relation extraction. We first present a general framework for biomedical relation extraction and then discuss the approaches proposed for binary and complex relation extraction with focus on the latter since it is a much more difficult task compared to binary relation extraction. Finally, we discuss challenges that we are facing with complex relation extraction and outline possible solutions and future directions.

Indexed as

BiologyData MiningHumansMedicine

Identifiers

PMID25214883
PMCPMC4156999
OpenAlexW2097352005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.