Evidence map›Paper›PMID 25214562›Full record

ArticleJournal of the National Cancer Institute2014

Deploying ibrutinib to lung cancer: another step in the quest towards drug repurposing.

Eric B Haura, Uwe Rix

Abstract readEditorialComment
In one paragraph

Article in Journal of the National Cancer Institute, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Characterization of Amorphous Ibrutinib Thermal Stability.Organic process research & development · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Eric B HauraDepartments of Thoracic Oncology (EBH) and Drug Discovery (UR), Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida. eric.haura@moffitt.org.
Uwe RixDepartments of Thoracic Oncology (EBH) and Drug Discovery (UR), Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.

Funding

SPORE in Lung CancerP50CA119997 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI GABRILOVICH, DMITRY I · 2008 to 2012
$11.0M
NCI NIH HHS P50 CA119997
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationAdenineAnimalsAntineoplastic AgentsCarcinoma, Non-Small-Cell LungErbB ReceptorsHumansLung NeoplasmsPiperidinesPyrazolesPyrimidinesAdenineAntineoplastic AgentsEGFR protein, humanErbB ReceptorsibrutinibPiperidinesPyrazolesPyrimidines

Identifiers

PMID25214562
PMCPMC5072366

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.