ReviewCurrent opinion in immunology2014
Diet, gut microbes, and genetics in immune function: can we leverage our current knowledge to achieve better outcomes in inflammatory bowel diseases?
Review in Current opinion in immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Sex hormones and gender differences in immune responses and anticancer immunity: a comprehensive review.Biologia futura · 2026Review
- Association between "Life's Critical 9" health score and the risk of inflammatory bowel disease: a prospective cohort study from the UK biobank.BMC public health · 2026Article
- Harnessing the Microbiome: A Comprehensive Review on Advancing Therapeutic Strategies for Rheumatic Diseases.Cureus · 2023Review
- MicrobiomeGWAS: A Tool for Identifying Host Genetic Variants Associated with Microbiome Composition.Genes · 2022Article
- Anti-TNF-α therapy alters the gut microbiota in proteoglycan-induced ankylosing spondylitis in mice.MicrobiologyOpen · 2019Article
- The Multifactorial Etiopathogeneses Interplay of Inflammatory Bowel Disease: An Overview.Gastrointestinal disorders (Basel, Switzerland) · 2019Article
- The role of diet in the aetiopathogenesis of inflammatory bowel disease.Nature reviews. Gastroenterology & hepatology · 2018Review
- Sex Hormones Determine Immune Response.Frontiers in immunology · 2018Review
- The Probiotic Effectiveness in Preventing Experimental Colitis Is Correlated With Host Gut Microbiota.Frontiers in microbiology · 2018Article
- Obesity in IBD: epidemiology, pathogenesis, disease course and treatment outcomes.Nature reviews. Gastroenterology & hepatology · 2017Review
- Long-term consumption of caffeine-free high sucrose cola beverages aggravates the pathogenesis of EAE in mice.Cell discovery · 2017Article
- Diet, gut microbes, and the pathogenesis of inflammatory bowel diseases.Molecular nutrition & food research · 2017Review
- Management of inflammatory bowel disease with oral serum-derived bovine immunoglobulin.Therapeutic advances in gastroenterology · 2015Article
- Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve?Expert review of clinical immunology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Autoimmune disorders, particularly inflammatory bowel diseases (IBD), are increasing at an alarming frequency. While the exact cause remains elusive, studies have examined how the immune system is shaped in the context of genetic susceptibility, gut microbes, and environmental pressures, including dietary intake. Shifts towards a Westernized high fat, high carbohydrate diet result in changes to gut microbiota structure and function that may aid in triggering and perpetuating autoimmunity by promoting the emergence of pathobionts leading to altered immune activation. This review summarizes our current understanding of dietary-induced changes in gut microbiota on autoimmunity in the context of IBD. We provide a framework for leveraging this knowledge to develop new dietary, microbial and immune-based modulation strategies for individualized risk assessment and improving clinical outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.