Evidence map›Paper›PMID 25213857›Full record

ArticleHealth and quality of life outcomes2014

Confirmatory factor analysis of the thyroid-related quality of life questionnaire ThyPRO.

Torquil Watt, Mogens Groenvold, Nina Deng, Barbara Gandek, Ulla Feldt-Rasmussen, Åse Krogh Rasmussen, Laszlo Hegedüs, Steen Joop Bonnema, Jakob Bue Bjorner

Abstract read
In one paragraph

Article in Health and quality of life outcomes, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Trial
  4. The compensatory enlargement of the remaining thyroid lobe following hemithyroidectomy is small and without impact on symptom relief.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018
    Trial
  5. Development and Validation of the Chinese Family Resilience Scale in Families in Hong Kong.International journal of environmental research and public health · 2023
    Article
  6. Review
  7. Article
  8. Primary hypothyroidism and quality of life.Nature reviews. Endocrinology · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Design of the Optimal Trial of Combination Therapy.Frontiers in endocrinology · 2020
    Article
  16. Exploring the item sets of the Recovering Quality of Life (ReQoL) measures using factor analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
    Article
  17. Article
  18. Article
  19. Conversion of standard retrospective patient-reported outcomes to momentary versions: cognitive interviewing reveals varying degrees of momentary compatibility.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Torquil Watt
Mogens Groenvold
Nina Deng
Barbara Gandek
Ulla Feldt-Rasmussen
Åse Krogh Rasmussen
Laszlo Hegedüs
Steen Joop Bonnema
Jakob Bue Bjorner

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimThyroid diseases are prevalent and chronic. With treatment, quality of life is restored in most, but not all patients. Construct validity of the thyroid-related quality of life questionnaire, ThyPRO, has been established by multi-trait scaling, but not evaluated with more elaborate methods. The purpose of the present study was to evaluate dimensionality of the ThyPRO scales and to attempt to understand possible item misfit through structural equation modeling for categorical data.

methodsThe current 85-item version of ThyPRO consists of 13 scales, covering domains of physical (4 scales) and mental (2 scales) symptoms, function and well-being (3 scales) and participation/social function (4 scales). The data were collected from a cross-sectional sample of 907 thyroid patients. One-factor confirmatory models were fitted to each scale, and evaluated by model fit statistics (comparative fit index >0.95, root mean square error of approximation <0.08), magnitude of factor loadings, model residual correlations and modification indices (MI). Indications of multi-dimensionality were tested in bi-factor models. Possible item misfit was evaluated in a combined, investigational model.

resultsEach ThyPRO scale was adequately represented by a unidimensional model after minor revisions. Eleven items were identified in the unidimensional models as potentially misfitting and were investigated further by multidimensional modeling.

conclusionElaborate psychometric modeling supported the construct validity of the ThyPRO. However, 11 potentially misfitting items and 18 items with local dependence to other items are candidates for removal in future item reduction processes.

Indexed as

Patient Outcome AssessmentQuality of LifeThyroid DiseasesActivities of Daily LivingAdultAgedCross-Sectional StudiesFactor Analysis, StatisticalFemaleHumansMaleMiddle AgedModels, StatisticalPersonal SatisfactionPsychometricsSocial Participation

Identifiers

PMID25213857
PMCPMC4172819

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.