ArticleEuropean journal of epidemiology2014
Obesity measures and risk of venous thromboembolism and myocardial infarction.
Article in European journal of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 5 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Association between waist-to-hip ratio and risk of myocardial infarction: a systematic evaluation and meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- Metabolic Disorders and Risk of Portal Vein Thrombosis in Liver Cirrhosis: A Systematic Review and Meta-Analysis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022Pooled it
- Waist-hip ratio as a predictor of myocardial infarction risk: A systematic review and meta-analysis.Medicine · 2018Pooled it
- Angiotensinogen-M235T as a risk factor for myocardial infarction in Asian populations: a genetic association study and a bioinformatics approach.Croatian medical journal · 2016Pooled it
- The sex-specific association between BMI and coronary heart disease: a systematic review and meta-analysis of 95 cohorts with 1·2 million participants.The lancet. Diabetes & endocrinology · 2015Pooled it
- Trial
- From body size to body composition: mechanisms linking obesity to venous thromboembolism.Journal of thrombosis and thrombolysis · 2026Article
- Metabolic syndrome and venous thromboembolism: the role of abdominal obesity and sex differences.Journal of thrombosis and thrombolysis · 2026Article
- Causal associations between diet and thromboembolism: A 2-sample Mendelian randomization study.Medicine · 2025Article
- The Interplay Between Obesity and Venous Thromboembolism: From Molecular Aspects to Clinical Issue.International journal of molecular sciences · 2025Review
- Venous thrombosis and obesity: from clinical needs to therapeutic challenges.Internal and emergency medicine · 2025Review
- Cohort Profile:Clinical epidemiology · 2025Article
- Identification of key risk factors for venous thromboembolism in urological inpatients based on the Caprini scale and interpretable machine learning methods.Thrombosis journal · 2024Article
- Review
- A combination of strongly associated prothrombotic single nucleotide polymorphisms could efficiently predict venous thrombosis risk.Frontiers in cardiovascular medicine · 2023Article
- Hand grip strength and risk of incident venous thromboembolism: The Tromsø study.Research and practice in thrombosis and haemostasis · 2022Article
- Joint effect of myocardial infarction and obesity on the risk of venous thromboembolism: The Tromsø Study.Journal of thrombosis and haemostasis : JTH · 2022Article
- Association of myocardial infarction and angina pectoris with obesity and biochemical indices in the South Korean population.Scientific reports · 2022Article
- Overall and abdominal obesity in relation to venous thromboembolism.Journal of thrombosis and haemostasis : JTH · 2021Article
- The Association of Waist Circumference and the Risk of Deep Vein Thrombosis.International journal of general medicine · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is a risk factor for arterial and venous thromboembolism. However, it is not known whether obesity mediates risk through shared mechanisms. In a population-based cohort, we aimed to compare the impact of obesity measures on risk of venous thromboembolism (VTE) and myocardial infarction (MI), and explore how obesity-related atherosclerotic risk factors influenced these relationships. Measures of body composition including body mass index , waist circumference (WC), hip circumference (HC), waist-hip ratio (WHR) and waist-to-height ratio (WHtR) were registered in 6,708 subjects aged 25-84 years, who participated in the Tromsø Study (1994-1995). Incident VTE- and MI-events were registered until January 1, 2011. There were 288 VTEs and 925 MIs during a median of 15.7 years of follow-up. All obesity measures were related to risk of VTE. In linear models, WC showed the highest risk estimates in both genders. In categorized models (highest versus lowest quintile), WC showed highest risk in men (HR 3.59; 95 % CI 1.82-7.06) and HC in women (HR 2.27; 95 % CI 1.54-4.92). Contrary, WHR and WHtR yielded the highest risk estimates for MI. The HR of MI (highest vs. lowest quintile) for WHR was 2.11 (95 % CI 1.59-2.81) in men and 1.62 (95 % CI 1.13-2.31) in women. The risk estimates for MI were substantially attenuated after adjustment for atherosclerotic risk factors, whereas the estimates for VTE remained unchanged. Our findings suggest that the impact of body fat distribution, and the causal pathway, differs for the association between obesity and arterial and venous thrombosis.
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