ArticleNaunyn-Schmiedeberg's archives of pharmacology2014
Common misconceptions about data analysis and statistics.
Article in Naunyn-Schmiedeberg's archives of pharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- The negative chronotropic effects of (±)-propranolol and (±)-4-NONaunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Why do probabilistic clinical models fail to transport between sites.NPJ digital medicine · 2024Review
- The roles, challenges, and merits of the p value.Patterns (New York, N.Y.) · 2023Review
- Is N-Hacking Ever OK? The consequences of collecting more data in pursuit of statistical significance.PLoS biology · 2023Article
- 6-Nitrodopamine potentiates contractions of rat isolated vas deferens induced by noradrenaline, adrenaline, dopamine and electric field stimulation.Naunyn-Schmiedeberg's archives of pharmacology · 2023Article
- Inhibition of uterine contractility by guanine-based purines in non-pregnant rats.Naunyn-Schmiedeberg's archives of pharmacology · 2023Article
- Preclinical Stroke Research and Translational Failure: A Bird's Eye View on Preventable Variables.Cellular and molecular neurobiology · 2022Review
- βNaunyn-Schmiedeberg's archives of pharmacology · 2022Article
- Genetic manipulation of trehalose-6-phosphate synthase results in changes in the soluble sugar profile in transgenic sugarcane stems.Plant direct · 2021Article
- Purinergic smooth muscle contractions in the human prostate: estimation of relevance and characterization of different agonists.Naunyn-Schmiedeberg's archives of pharmacology · 2021Article
- Improving target assessment in biomedical research: the GOT-IT recommendations.Nature reviews. Drug discovery · 2021Review
- The STK16 inhibitor STK16-IN-1 inhibits non-adrenergic and non-neurogenic smooth muscle contractions in the human prostate and the human male detrusor.Naunyn-Schmiedeberg's archives of pharmacology · 2020Article
- Expression of a Small Ubiquitin-Like Modifier Protease Increases Drought Tolerance in Wheat (Frontiers in plant science · 2019Article
- Characterization of differential patient profiles and therapeutic responses of pharmacy customers for four ambroxol formulations.BMC pharmacology & toxicology · 2018Observational
- Review
- The Use ofFrontiers in veterinary science · 2018Review
- KNaunyn-Schmiedeberg's archives of pharmacology · 2017Article
- Factors associated with efficacy of an ibuprofen/pseudoephedrine combination drug in pharmacy customers with common cold symptoms.International journal of clinical practice · 2017Article
- Naunyn-Schmiedeberg's Archives of Pharmacology under new editorship: change and continuity.Naunyn-Schmiedeberg's archives of pharmacology · 2016Article
- Preclinical research strategies for newly approved drugs as reflected in early publication patterns.Naunyn-Schmiedeberg's archives of pharmacology · 2016Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ideally, any experienced investigator with the right tools should be able to reproduce a finding published in a peer-reviewed biomedical science journal. In fact, the reproducibility of a large percentage of published findings has been questioned. Undoubtedly, there are many reasons for this, but one reason maybe that investigators fool themselves due to a poor understanding of statistical concepts. In particular, investigators often make these mistakes: 1. P-Hacking. This is when you reanalyze a data set in many different ways, or perhaps reanalyze with additional replicates, until you get the result you want. 2. Overemphasis on P values rather than on the actual size of the observed effect. 3. Overuse of statistical hypothesis testing, and being seduced by the word "significant". 4. Overreliance on standard errors, which are often misunderstood.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.