Evidence map›Paper›PMID 25211508›Full record

ArticleJournal of cellular biochemistry2015

Pediatric brain tumor cell lines.

Jingying Xu, Ashley Margol, Shahab Asgharzadeh, Anat Erdreich-Epstein

Abstract read
In one paragraph

Article in Journal of cellular biochemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Review
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  6. Review
  7. Up-Regulation ofCell journal · 2021
    Article
  8. Article
  9. Article
  10. Review
  11. Frontiers in oncology · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jingying XuDivision of Hematology, Oncology and Blood & Marrow Transplantation, Department of Pediatrics, Children's Hospital Los Angeles and the Keck School of Medicine, University of Southern California, Los Angeles, California, 90027.
Ashley Margol
Shahab Asgharzadeh
Anat Erdreich-Epstein

Funding

Tumor-Inhibitory Effects of P1D1 in GliomasR21NS077007 · NINDS · CHILDREN'S HOSPITAL OF LOS ANGELES · PI ERDREICH-EPSTEIN, ANAT · 2011 to 2012
$440k
NINDS NIH HHS NS077007NINDS NIH HHS R21 NS077007
6 · The paper itself

Abstract

Pediatric brain tumors as a group, including medulloblastomas, gliomas, and atypical teratoid rhabdoid tumors (ATRT) are the most common solid tumors in children and the leading cause of death from childhood cancer. Brain tumor-derived cell lines are critical for studying the biology of pediatric brain tumors and can be useful for initial screening of new therapies. Use of appropriate brain tumor cell lines for experiments is important, as results may differ depending on tumor properties, and can thus affect the conclusions and applicability of the model. Despite reports in the literature of over 60 pediatric brain tumor cell lines, the majority of published papers utilize only a small number of these cell lines. Here we list the approximately 60 currently-published pediatric brain tumor cell lines and summarize some of their central features as a resource for scientists seeking pediatric brain tumor cell lines for their research.

Indexed as

AdolescentBrain NeoplasmsCell Line, TumorChildChild, PreschoolEpendymomaFemaleGene AmplificationGlioblastomaHumansInfantMaleMedulloblastomaMutationOtx Transcription FactorsProto-Oncogene Proteins c-mycMYC protein, humanOTX2 protein, humanOtx Transcription FactorsProto-Oncogene Proteins c-mycTumor Suppressor Protein p53ATRTEPENDYMOMAGLIOMAMEDULLOBLASTOMAPEDIATRIC BRAIN TUMOR CELL LINES

Identifiers

PMID25211508
PMCPMC10656279

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.