Evidence map›Paper›PMID 25211176›Full record

ArticleThe Journal of investigative dermatology2015

Determinants of vitamin D status in Caucasian adults: influence of sun exposure, dietary intake, sociodemographic, lifestyle, anthropometric, and genetic factors.

Mathilde Touvier, Mélanie Deschasaux, Marion Montourcy, Angela Sutton, Nathalie Charnaux, Emmanuelle Kesse-Guyot, Karen E Assmann, Léopold Fezeu, Paule Latino-Martel, Nathalie Druesne-Pecollo and 8 more

Abstract read
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In one paragraph

Article in The Journal of investigative dermatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 4 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 4 syntheses or guidelines pooled it, 159 citations in OpenAlex.

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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 1 country.

Mathilde TouvierSorbonne Paris Cité Epidemiology and Biostatistics Research Center (CRESS), Nutritional Epidemiology Research Team (EREN), Inserm U1153, Inra U1125, Cnam, Paris 13 University, Paris 5 University, Paris 7 University, Bobigny, France. Electronic address: m.touvier@eren.smbh.univ-paris13.fr.
Mélanie DeschasauxSorbonne Paris Cité Epidemiology and Biostatistics Research Center (CRESS), Nutritional Epidemiology Research Team (EREN), Inserm U1153, Inra U1125, Cnam, Paris 13 University, Paris 5 University, Paris 7 University, Bobigny, France.
Marion MontourcySorbonne Paris Cité Epidemiology and Biostatistics Research Center (CRESS), Nutritional Epidemiology Research Team (EREN), Inserm U1153, Inra U1125, Cnam, Paris 13 University, Paris 5 University, Paris 7 University, Bobigny, France.
Angela SuttonBiochemistry Department, Jean Verdier Hospital, Inserm U698, Paris 13 University, Bondy, France.
Nathalie CharnauxBiochemistry Department, Jean Verdier Hospital, Inserm U698, Paris 13 University, Bondy, France.
Emmanuelle Kesse-GuyotSorbonne Paris Cité Epidemiology and Biostatistics Research Center (CRESS), Nutritional Epidemiology Research Team (EREN), Inserm U1153, Inra U1125, Cnam, Paris 13 University, Paris 5 University, Paris 7 University, Bobigny, France.
Karen E AssmannSorbonne Paris Cité Epidemiology and Biostatistics Research Center (CRESS), Nutritional Epidemiology Research Team (EREN), Inserm U1153, Inra U1125, Cnam, Paris 13 University, Paris 5 University, Paris 7 University, Bobigny, France.
Léopold FezeuSorbonne Paris Cité Epidemiology and Biostatistics Research Center (CRESS), Nutritional Epidemiology Research Team (EREN), Inserm U1153, Inra U1125, Cnam, Paris 13 University, Paris 5 University, Paris 7 University, Bobigny, France.
Paule Latino-MartelSorbonne Paris Cité Epidemiology and Biostatistics Research Center (CRESS), Nutritional Epidemiology Research Team (EREN), Inserm U1153, Inra U1125, Cnam, Paris 13 University, Paris 5 University, Paris 7 University, Bobigny, France.
Nathalie Druesne-PecolloSorbonne Paris Cité Epidemiology and Biostatistics Research Center (CRESS), Nutritional Epidemiology Research Team (EREN), Inserm U1153, Inra U1125, Cnam, Paris 13 University, Paris 5 University, Paris 7 University, Bobigny, France.
Christiane GuinotResearch Centre on Human Skin of CHANEL (CERIES), Neuilly sur Seine, France; Computer Science Laboratory, François Rabelais University, Tours, France.
Julie LatreilleSorbonne Paris Cité Epidemiology and Biostatistics Research Center (CRESS), Nutritional Epidemiology Research Team (EREN), Inserm U1153, Inra U1125, Cnam, Paris 13 University, Paris 5 University, Paris 7 University, Bobigny, France; Research Centre on Human Skin of CHANEL (CERIES), Neuilly sur Seine, France.
Denis MalvyDermatology Department, Saint André Hospital, Bordeaux, France.
Pilar GalanSorbonne Paris Cité Epidemiology and Biostatistics Research Center (CRESS), Nutritional Epidemiology Research Team (EREN), Inserm U1153, Inra U1125, Cnam, Paris 13 University, Paris 5 University, Paris 7 University, Bobigny, France.
Serge HercbergSorbonne Paris Cité Epidemiology and Biostatistics Research Center (CRESS), Nutritional Epidemiology Research Team (EREN), Inserm U1153, Inra U1125, Cnam, Paris 13 University, Paris 5 University, Paris 7 University, Bobigny, France; Public Health Department, Avicenne Hospital, Bobigny, France.
Sigrid Le ClercConservatoire National des Arts et Métiers (CNAM), Genomics, Bioinformatics and Applications Team (EA4627), Paris, France.
Jean-Claude SouberbielleDepartment of Physiology, Necker Hospital, INSERM U845, Paris, France.
Khaled EzzedineSorbonne Paris Cité Epidemiology and Biostatistics Research Center (CRESS), Nutritional Epidemiology Research Team (EREN), Inserm U1153, Inra U1125, Cnam, Paris 13 University, Paris 5 University, Paris 7 University, Bobigny, France; Dermatology Department, Saint André Hospital, Bordeaux, France.
Université Paris Cité · FRInserm · FRSorbonne Université · FRUniversité Sorbonne Paris Nord · FRCentre de Recherche Épidémiologie et StatistiqueConservatoire National des Arts et Métiers · FRHôpital Saint-André · FRUniversité de Tours · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Very few studies have investigated the determinants of serum vitamin D levels using a set of variables that include simultaneously sun exposure, phototype, dietary intake, sociodemographics, anthropometric, lifestyle data, and genetic polymorphisms. Our objective was to investigate the associations between all these parameters and vitamin D status in a large sample of French adults. This cross-sectional survey was based on 1,828 middle-aged Caucasian adults from the SU.VI.MAX (SUpplémentation en VItamines et Minéraux AntioXydants) study. Plasma 25-hydroxyvitamin D (25OHD) concentration was lower among women (P<0.0001), older subjects (P=0.04), obese/underweight (P<0.0001), those living at higher latitudes (P<0.0001), those whose blood draw occurred in early spring (P<0.0001), less physically active (P<0.0001), with low sun exposure (P<0.0001), and with no-to-low alcohol intake (P=0.0001). Mutant GC rs4588 and rs7041 single nucleotide polymorphisms were associated with lower and higher 25OHD concentrations, respectively (P<0.0001). Dietary intake was not a major determinant of vitamin D status (P=0.7). This study provides an overall picture of determinants of vitamin D status. Several modifiable factors were identified, such as daily-life moderate sun exposure, physical activity, and normal-weight maintenance, which should be targeted by public health policies in order to improve vitamin D status in the general population, while avoiding active/intensive sun exposure, in line with recommendations for skin cancer prevention.

Indexed as

SunlightAdultAgedBody WeightCross-Sectional StudiesFemaleHumansLife StyleMaleMiddle AgedParathyroid HormonePolymorphism, Single NucleotideReceptors, CalcitriolVitamin D25-hydroxyvitamin DParathyroid HormoneReceptors, CalcitriolVitamin D

Identifiers

PMID25211176
OpenAlexW2083281693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.