ArticlePloS one2014
The ocular benefits of estrogen replacement therapy: a population-based study in postmenopausal Korean women.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- The Association of Female Reproductive Factors with Glaucoma and Related Traits: A Systematic Review.Ophthalmology. GlaucomaPooled it
- Alterations in tear function and meibomian gland dysfunction across various phenotypes of polycystic ovary syndrome.Scientific reports · 2025Article
- Estrogen dysregulation, intraocular pressure, and glaucoma risk.Experimental eye research · 2023Review
- Hysterectomy for Benign Indications and Risk of Cataract Formation in South Korean Women.Medicina (Kaunas, Lithuania) · 2023Article
- Effects of Androgens on the Thickness of Retinal Layers in Transgender Men and in Women with Polycystic Ovarian Syndrome.Transgender health · 2023Article
- Sex Hormones, Growth Hormone, and the Cornea.Cells · 2022Review
- Girl Power in Glaucoma: The Role of Estrogen in Primary Open Angle Glaucoma.Cellular and molecular neurobiology · 2022Review
- Reproductive risk factors of pterygium in postmenopausal women: a nationwide study in the Republic of Korea.Scientific reports · 2021Article
- Tear proteomic profile in three distinct ocular surface diseases: keratoconus, pterygium, and dry eye related to graft-versus-host disease.Clinical proteomics · 2020Article
- [Gender medicine in ophthalmology : The "small difference" between women and men].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020Article
- Females with Type 2 Diabetes Mellitus Are Prone to Diabetic Retinopathy: A Twelve-Province Cross-Sectional Study in China.Journal of diabetes research · 2020Article
- Eye diseases in women.Fukushima journal of medical science · 2019Review
- Distribution and Characteristics of Meibomian Gland Dysfunction Subtypes: A Multicenter Study in South Korea.Korean journal of ophthalmology : KJO · 2019Article
- Prevalence and risk factors for pterygium: a cross-sectional study in Han and Manchu ethnic populations in Hebei, China.BMJ open · 2019Article
- Gonadal Hormones and Retinal Disorders: A Review.Frontiers in endocrinology · 2018Review
- The Association between Female Reproductive Factors and Open-Angle Glaucoma in Korean Women: The Korean National Health and Nutrition Examination Survey V.Journal of ophthalmology · 2018Article
- Calycosin Orchestrates Osteogenesis of Danggui Buxue Tang in Cultured Osteoblasts: Evaluating the Mechanism of Action by Omics and Chemical Knock-out Methodologies.Frontiers in pharmacology · 2018Article
- Protective effect ofAnatomy & cell biology · 2017Article
- Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample.Menopause (New York, N.Y.) · 2017Article
- Anterior Segment Findings in Women with Polycystic Ovary Syndrome.Turkish journal of ophthalmology · 2017Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo elucidate the prevalence of cataract, glaucoma, pterygia, and diabetic retinopathy among Korean postmenopausal women with or without estrogen replacement therapy (ERT).
methodsA cross-sectional, nationally representative sample from the 4th Korea National Health and Nutrition Examination Survey (KNHANES IV) (2007-2009) was used. Participants were interviewed for the determination of socioeconomic and gynecologic factors. Each woman also underwent an ophthalmologic examination and provided a blood sample for risk factor assessment.
resultsOf 3968 postmenopausal women enrolled, 3390 had never received estrogen, and 578 were undergoing estrogen treatment. After adjusting for age, diabetes, hypertension, high cholesterol levels, and high low-density lipoprotein levels, the prevalence of anterior polar cataract, retinal nerve fiber layer (RNFL) defect, and flesh pterygium was higher in the non-ERT group (OR, 3.24; 95% CI, 1.12-9.35, OR 1.70; 95% CI, 1.04-2.78, OR 3.725; 95% CI, 1.21-11.45, respectively). Further, the prevalence of atrophic pterygium was lower in the non-ERT group compared to that in the ERT group (OR, 0.21, 95% CI, 0.07-0.63).
conclusionsThese data suggest that ERT has a protective effect against the development of anterior polar cataract, flesh pterygium, and RNFL defect.
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