ReviewJournal of exercise rehabilitation2014
Cellular mechanism of eccentric-induced muscle injury and its relationship with sarcomere heterogeneity.
Review in Journal of exercise rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 6 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Effects of Plyometric Jump Training on the Reactive Strength Index in Healthy Individuals Across the Lifespan: A Systematic Review with Meta-analysis.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- The effects of plyometric jump training on physical fitness attributes in basketball players: A meta-analysis.Journal of sport and health science · 2022Pooled it
- Effects of Plyometric Jump Training on Physical Fitness in Amateur and Professional Volleyball: A Meta-Analysis.Frontiers in physiology · 2021Pooled it
- Effects of Plyometric Jump Training on Balance Performance in Healthy Participants: A Systematic Review With Meta-Analysis.Frontiers in physiology · 2021Pooled it
- Effects of Plyometric Jump Training on Jump and Sprint Performance in Young Male Soccer Players: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- Effect of low-level phototherapy on delayed onset muscle soreness: a systematic review and meta-analysis.Lasers in medical science · 2016Pooled it
- Supplementation with a Bioactive Melon Concentrate in Humans and Animals: Prevention of Oxidative Damages and Fatigue in the Context of a Moderate or Eccentric Physical Activity.International journal of environmental research and public health · 2020Trial
- CombinedFrontiers in physiology · 2025Article
- Predicting the Clean Movement Technique in CrossfitInternational journal of environmental research and public health · 2022Article
- The Influence of Phototherapy on Recovery From Exercise-Induced Muscle Damage.International journal of sports physical therapy · 2022Article
- FOAM ROLLING AND INDICES OF AUTONOMIC RECOVERY FOLLOWING EXERCISE-INDUCED MUSCLE DAMAGE.International journal of sports physical therapy · 2020Article
- Regeneration of Skeletal Muscle After Eccentric Injury.Journal of sport rehabilitation · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Activity-induced muscle injury and dysfunction have been identified as key components of musculoskeletal injuries. These injuries often occur following eccentric contractions, when the muscle is under tension and stretched by a force that is greater than the force generated by the muscle. Many daily activities require muscles to perform eccentric contractions, including walking (or running) downhill or down stairs, lowering heavy objects, and landing from a jump. Injuries often occur when these activities are performed at high intensity or for prolonged periods of time. General features of eccentric-induced muscle injury are well documented and include disruption of intracellular muscle structure, prolonged muscle weakness and dysfunction, a delayed-onset muscle soreness, and inflammation. Several weeks are required for the affected tissue to fully regenerate and recover from eccentric-induced muscle injury. Possible mechanisms responsible for eccentric-induced muscle injury are activation impairment and structural disruption of the sarcomere. These two factors seem to be the main sources of eccentric-induced muscle injury. Rather than being separate mechanisms they may be complimentary and interact with each other. Therefore, in this review we will focus on the two main cellular mechanism of muscle cell injury following accustomed eccentric contraction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.