Evidence map›Paper›PMID 25210666›Full record

ArticleSpringerPlus2014

Fusarium napiforme systemic infection: case report with molecular characterization and antifungal susceptibility tests.

Marcela de Souza, Tetsuhiro Matsuzawa, Luzia Lyra, Ariane Fidelis Busso-Lopes, Tohru Gonoi, Angélica Zaninele Schreiber, Katsuhiko Kamei, Maria Luiza Moretti, Plínio Trabasso

Abstract read
In one paragraph

Article in SpringerPlus, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Unpredictable susceptibility of emerging clinical moulds to tri-azoles: review of the literature and upcoming challenges for mould identification.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marcela de SouzaDepartment of Internal Medicine, School of Medicine, University of Campinas, Campinas, São Paulo Brazil ; LIM 46 - Laboratory of Parasitology - HC/FMUSP, Kragujevac, São Paulo Brazil.
Tetsuhiro MatsuzawaMedical Mycology Research Center, Chiba University, Chiba, Japan.
Luzia LyraDepartment of Clinical Pathology, School of Medicine, University of Campinas, Campinas, São Paulo Brazil.
Ariane Fidelis Busso-LopesDepartment of Internal Medicine, School of Medicine, University of Campinas, Campinas, São Paulo Brazil.
Tohru GonoiMedical Mycology Research Center, Chiba University, Chiba, Japan.
Angélica Zaninele SchreiberDepartment of Clinical Pathology, School of Medicine, University of Campinas, Campinas, São Paulo Brazil.
Katsuhiko KameiMedical Mycology Research Center, Chiba University, Chiba, Japan.
Maria Luiza MorettiDepartment of Internal Medicine, School of Medicine, University of Campinas, Campinas, São Paulo Brazil.
Plínio TrabassoDepartment of Internal Medicine, School of Medicine, University of Campinas, Campinas, São Paulo Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDuring the last decades, Fusarium spp. has been reported as a significant cause of disease in humans, especially in immunocompromised patients, who have high risk of invasive life-threatening disease. Fusarium species usually reported as cause of human disease are F. solani, F. oxysporum and F. verticillioides. CASE DESCRIPTION: We describe the second case in the literature of disseminated fusariosis caused by Fusarium napiforme, that occurred in a 60-year-old woman with multiple myeloma after subsequent cycles of chemotherapy. DISCUSSION AND EVALUATION: We identified the F. napiforme not only by standard morphologic criteria by macroscopic and microscopic characteristics, but also confirmed by molecular biology methods, including sequencing. The antifungal susceptibility of the F. napiforme isolates were tested to seven antifungal drugs; the azoles were the most active drug against all the isolates tested.

conclusionsFusarium spp. are of relevance in medical mycology, and their profiles of low susceptibility to antifungal drugs highlight the importance for faster and more accurate diagnostic tests, what can contribute to an earlier and precise diagnosis and treatment.

Indexed as

FusariosisImmunocompromised hostOpportunistic Infections

Identifiers

PMID25210666
PMCPMC4159480

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.