ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada2014
The role of preoperative prophylactic antibiotics in hypospadias repair.
Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- The effect of the use of postoperative antibiotic prophylaxis compared with non-use for stented distal hypospadias repair wound: A meta-analysis.International wound journal · 2023Pooled it
- The effect of the cortical bone trajectory screw fixation and traditional pedicle screw fixation on surgical site wound infection in posterior lumbar fusion wound: A meta-analysis.International wound journal · 2023Pooled it
- Do Perioperative Antibiotics Improve Outcomes After Hypospadias Repair? A Systematic Review and Meta-Analysis of Pediatric Literature.Children (Basel, Switzerland) · 2026Review
- Antibiotic Prophylaxis with Trimethoprim-Sulfamethoxazole versus No Treatment after Mid-to-Distal Hypospadias Repair: A Prospective, Randomized Study.Advances in urology · 2018Article
- Prophylactic Antibiotics After Stented, Distal Hypospadias Repair: Randomized Pilot Study.Global pediatric health · 2018Article
- Prophylactic antibiotic use in pediatric patients undergoing urinary tract catheterization: a survey of members of the Society for Pediatric Urology.BMC urology · 2017Article
- Antibiotic prophylaxis in hypospadias repair: It's time to re-evaluate.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2014Article
- Antibiotics or No Antibiotics after Urethroplasty For Hypospadias: An RCT Evaluating Short Term Surgical Outcomes.Journal of Indian Association of Pediatric SurgeonsArticle
- Current hypospadias management: Diagnosis, surgical management, and long-term patient-centred outcomes.Canadian Urological Association journal = Journal de l'Association des urologues du CanadaReview
- A useful tip for preventing surgical site infections after hypospadias repair. A single surgeon's experience of 376 cases.African journal of paediatric surgery : AJPSArticle
- Outcome of restricted antibiotic policy in a tertiary-level paediatric surgical unit.African journal of paediatric surgery : AJPSArticle
- Optimizing neourethral coverage in urethroplasty for hypospadias with tunica vaginalis versus dartos fascia: A systematic review and meta-analysis.Tzu chi medical journalArticle
- To Compare Short-term Surgical Outcome among Patients given Continuous Postoperative Antibiotic Prophylaxis and those given no Postoperative Antibiotics after Urethroplasty for Hypospadias: A Pilot Study.Journal of Indian Association of Pediatric SurgeonsArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWe sought to determine whether the use of preoperative antibiotics is effective in reducing postoperative wound infections and urinary tract infections (UTI) in hypospadias repair.
methodsWe retrospectively reviewed all hypospadias repairs performed at the Montreal Children's Hospital between March 2009 and September 2012. All types of primary hypospadias repairs and redo cases were included. Patients with no adequate follow-up or with missing records of antibiotics were excluded. Preoperative antibiotics were given in the form of cefazolin (50 mg/kg intravenously) when appropriate. Postoperative oral antibiotics were administered as decided by the pediatric urologist. Primary outcomes included postoperative wound infection and UTI. Secondary outcomes included the need for reoperation of hypospadias due to urethrocutaneous fistula, meatal stenosis, urethral stricture and wound dehiscence.
resultsIn total, 157 cases of hypospadias repair were reviewed; of these 7 were excluded due to lack of follow-up. Of the remaining 150 patients, 62 received preoperative antibiotics and 88 did not. The groups were well-matched for age, hypospadias characteristics, type of repair and repair of curvature. The group that received preoperative antibiotics had a significantly higher number of stented cases (82% vs. 52% of the non-preoperative antibiotic group). Two cases of wound infection were reported (1 in the pre-operative antibiotic group and 1 in the non-preoperative antibiotic group). There was no symptomatic UTI or culture-demonstrated UTI in either group. Moreover, there was no statistically significant difference between the 2 groups in terms of primary outcomes. The complication rate was 11% (17/150 repairs) and all patients needed reoperation. This study's important limitations include the rarity of studied end points combined with the small sample and the retrospective nature of our study.
conclusionOur findings do not support the routine use of preoperative antibiotics in hypospadias repair.
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