ArticleKorean journal of pediatrics2014
A pediatric case of Brugada syndrome diagnosed by fever-provoked ventricular tachycardia.
Article in Korean journal of pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 6 citations in OpenAlex.
- Ion Channel Diseases as a Cause of Sudden Cardiac Death in Young People: Aspects of Their Diagnosis, Treatment, and Pathogenesis.Deutsches Arzteblatt international · 2024Review
- A de novo BRPF1 variant in a case of Sudden Unexplained Death in Childhood.European journal of medical genetics · 2020Article
- Fever Unmasked Brugada Syndrome in Pediatric Patient: A Case Report.Clinical practice and cases in emergency medicine · 2020Article
- A New Approach to Rare Diseases of Children: The Undiagnosed Diseases Network.The Journal of pediatrics · 2018Article
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Authors and funding
6 authors at 3 institutions in 1 country.
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Abstract
Brugada syndrome is a rare channelopathy associated with the SCN5A gene that causes fatal ventricular arrhythmias. This case of Brugada syndrome, in which ventricular tachycardia (VT) was provoked by high fever, is the first report in a Korean child. The boy had retinoblastoma of his left eye diagnosed at 16 months of age. After chemotherapy, he contracted a catheter-related infection with a high fever up to 41℃ leading to monomorphic VT. This was characterized as having right bundle branch block morphology, superior axis deviation, and a heart rate of 212/min. Direct current cardioversion recovered the VT to sinus rhythm after a lack of response to amiodarone and lidocaine. A second attack of VT that was not controlled by cardioversion, however, responded to lidocaine. The baseline electrocardiogram showed a long PR interval and QRS duration, and the patient's grandfather had a history of Brugada syndrome. A mutation in SCN5A was identified in this patient, his father, and his grandfather. The patient was treated with quinidine and followed up for 1 year.
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