ReviewInternational journal of chronic obstructive pulmonary disease2014
Epidemiology and clinical impact of major comorbidities in patients with COPD.
Review in International journal of chronic obstructive pulmonary disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05947253 (Comparative Effects of BBT and Active Cycle of Breathing Technique on Dyspnea and Quality of Life in COPD), which is not on this map. Cited by 201 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Effects of BBT and Active Cycle of Breathing Technique on Dyspnea and Quality of Life in COPD
Who cites it
201 citing papers in PubMed, 7 syntheses or guidelines pooled it, 410 citations in OpenAlex.
- Association between mental health and chronic obstructive pulmonary disease (COPD) outcomes: systematic review and meta-analysis.BMJ open respiratory research · 2026Pooled it
- Modifiable risk factors that may be addressed in routine care to prevent progression to and extension of multimorbidity in people with COPD: a systematic literature review.BMJ open respiratory research · 2024Pooled it
- Prevalence of lung cancer in chronic obstructive pulmonary disease: A systematic review and meta-analysis.Frontiers in oncology · 2022Pooled it
- Effectiveness of Proton-Pump Inhibitors in Chronic Obstructive Pulmonary Disease: A Meta-Analysis of Randomized Controlled Trials.Frontiers in medicine · 2022Pooled it
- Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one other long-term condition: a mixed methods review.The Cochrane database of systematic reviews · 2021Pooled it
- Effect of periodontal therapy on COPD outcomes: a systematic review.BMC pulmonary medicine · 2021Pooled it
- Lung volume reduction surgery for diffuse emphysema.The Cochrane database of systematic reviews · 2016Pooled it
- Trial
- Effects of Ninjin'yoeito on Patients with Chronic Obstructive Pulmonary Disease and Comorbid Frailty and Sarcopenia: A Preliminary Open-Label Randomized Controlled Trial.International journal of chronic obstructive pulmonary disease · 2024Trial
- Inhalation therapies in COPD - adverse drug reactions impact on emergency department presentations.European journal of clinical pharmacology · 2023Trial
- Clinical Observation of General Anesthesia Combined with Spinal Anesthesia in Elderly Patients with Chronic Obstructive Pulmonary Disease.BioMed research international · 2022Trial
- Enhanced External Counterpulsation Efficacy on Exercise Endurance in COPD Patients and Healthy Subjects: A Pilot Randomized Clinical Trial.International journal of chronic obstructive pulmonary disease · 2020Trial
- Thoracic Kyphosis on Chest CT Scans Is Associated With Incident Vertebral Fractures in Smokers.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019Trial
- The Japanese Society of Hypertension Practical Consensus Guidelines for Seasonal Blood Pressure Management.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Predictive ability of the COPD-specific comorbidity test (COTE) score versus the Charlson comorbidity index (CCI) in patients with COPD.BMJ open respiratory research · 2026Article
- The relevance of sputum galectin-7 levels to clinical and prognostic factors in patients with chronic obstructive pulmonary disease: a prospective cohort study from China.BMC pulmonary medicine · 2026Observational
- Association between a novel nutritional index and coronary heart disease in COPD patients: a retrospective study in China.BMC pulmonary medicine · 2026Article
- Risk factors for COPD exacerbations and mortality, and variation between primary care settings: the PRAXIS cohort study in Sweden.Family medicine and community health · 2026Article
- Ultrasound measurements of pelvic floor and diaphragm muscles in chronic obstructive pulmonary disease patients with urinary incontinence.Irish journal of medical science · 2026Article
- COPD and vitamin K antagonism: a cohort study of 1-year all-cause mortality and risk of hospitalisation due to a severe exacerbation.BMJ open respiratory research · 2026Observational
141 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Comorbidities are frequent in chronic obstructive pulmonary disease (COPD) and significantly impact on patients' quality of life, exacerbation frequency, and survival. There is increasing evidence that certain diseases occur in greater frequency amongst patients with COPD than in the general population, and that these comorbidities significantly impact on patient outcomes. Although the mechanisms are yet to be defined, many comorbidities likely result from the chronic inflammatory state that is present in COPD. Common problems in the clinical management of COPD include recognizing new comorbidities, determining the impact of comorbidities on patient symptoms, the concurrent treatment of COPD and comorbidities, and accurate prognostication. The majority of comorbidities in COPD should be treated according to usual practice, and specific COPD management is infrequently altered by the presence of comorbidities. Unfortunately, comorbidities are often under-recognized and under-treated. This review focuses on the epidemiology of ten major comorbidities in patients with COPD. Further, we emphasize the clinical impact upon prognosis and management considerations. This review will highlight the importance of comorbidity identification and management in the practice of caring for patients with COPD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.