ArticleIndian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India2014
Effect of duration of fasting and diet on the myocardial uptake of F-18-2-fluoro-2-deoxyglucose (F-18 FDG) at rest.
Article in Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed.
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- Positron emission tomography and magnetic resonance imaging of the brain in experimental human malaria, a prospective cohort study.Scientific reports · 2022Article
- Various Aspects of Fasting on the Biodistribution of Radiopharmaceuticals.Current drug metabolism · 2022Review
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- Gallium-68 DOTANOC scan in a patient with suspected cardiac sarcoidosis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Optimizing myocardial metabolism for fluorine-18 fluorodeoxyglucose positron emission tomography imaging of cardiac inflammation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Status of F-18 fluorodeoxyglucose uptake in normal and hibernating myocardium after glucose and insulin loading.Journal of the Saudi Heart Association · 2018Article
- Searching for novel PET radiotracers: imaging cardiac perfusion, metabolism and inflammation.American journal of nuclear medicine and molecular imaging · 2018Review
- Patient preparation for cardiac fluorine-18 fluorodeoxyglucose positron emission tomography imaging of inflammation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- The effects of 18-h fasting with low-carbohydrate diet preparation on suppressed physiological myocardial (18)F-fluorodeoxyglucose (FDG) uptake and possible minimal effects of unfractionated heparin use in patients with suspected cardiac involvement sarcoidosis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Assessment of atherosclerosis in large vessel walls: A comprehensive review of FDG-PET/CT image acquisition protocols and methods for uptake quantification.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Review
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Abstract
contextPatterns of myocardial fluoro-2-deoxyglucose (FDG) uptake with respect to duration of fasting and dietary modifications.
aimWe observed the effect of duration of fasting and diet on the myocardial uptake pattern of F-18 FDG in patients routinely referred for oncological evaluation and no previous history of Coronary Artery Disease (CAD). SETTINGS AND
designProspective study. SUBJECTS AND
methodsA total of 153 patients (M: 81, F: 72; mean age: 47 ± 15 years; mean blood glucose level (mBG) 105 ± 23 mg/dl) were randomly divided in three groups. Group A: 4-6 h fasting; Group B: Overnight fasting (12-14 h); Group C: Low carbohydrate and fat rich diet for 2 days coupled with overnight fasting prior to the positron emission tomography (PET) scan. FDG uptake was classified as following: 1) homogeneous uptake, 2) heterogeneous uptake, and 3) 'no uptake' in the left ventricular (LV) myocardium. FDG PET study was performed as standard protocol for oncological conditions. STATISTICAL ANALYSIS USED: Descriptive statistics, Chi-square test or Fisher's exact test, and Spearman's rank correlation tests were applied.
resultsWe observed the 'no uptake' pattern in five (10%), 28 (55%), and 39 (77%), 'heterogeneous' pattern in 20 (39%), 14 (28%), and seven (14%), and 'homogeneous' pattern in 26 (51%), nine (18%), and five (10%) patients in Group A, B, and C, respectively. There was statistically significant difference of myocardial uptake pattern between group A and B (P < 0.0001), between group A and C (P < 0.0001), and between Group B and C (P = 0.023). The mBG was 102, 105, and 111 mg/dl in 'no uptake', heterogeneous, and homogeneous uptake pattern, respectively, (P = 0.103). Also, within each group the mBG was not related to the uptake pattern.
conclusionBoth restricted diet and duration of fasting play an important role in determining the pattern and suppression of myocardial F-18 FDG uptake. Overnight fasting and restricted diet together suppress myocardial FDG uptake more than overnight fasting alone, which suppresses uptake more than 4-h fasting.
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