Evidence map›Paper›PMID 25209429›Full record

ArticleAngewandte Chemie (International ed. in English)2014

Radical C-H functionalization of heteroarenes under electrochemical control.

Alexander G O'Brien, Akinobu Maruyama, Yasuhide Inokuma, Makoto Fujita, Phil S Baran, Donna G Blackmond

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Photoelectrochemical Iron(III) Catalysis for Late-Stage C─H Fluoroalkylations.Angewandte Chemie (International ed. in English) · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. A Perspective on Late-Stage Aromatic C-H Bond Functionalization.Journal of the American Chemical Society · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexander G O'BrienDepartment of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 (USA).
Akinobu Maruyama
Yasuhide Inokuma
Makoto Fujita
Phil S Baran
Donna G Blackmond

Funding

Preparative Radical Chemistry for Biomedical ResearchR01GM106210 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI BARAN, PHIL S · 2013 to 2016
$2.1M
NIGMS NIH HHS GM 106210NIGMS NIH HHS R01 GM106210
6 · The paper itself

Abstract

Electrochemical reactions are shown to be effective for the C-H functionalization of a number of heterocyclic substrates that are recalcitrant to conventional peroxide radical initiation conditions. Monitoring reaction progress under electrochemical conditions provides mechanistic insight into the C-H functionalization of a series of heterocycles of interest in medicinal chemistry.

Indexed as

CarbonHeterocyclic CompoundsHydrogenCarbonHeterocyclic CompoundsHydrogenCH activationelectrochemistryheterocyclesradical reactionsreaction mechanisms

Identifiers

PMID25209429
PMCPMC4214156

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.