Evidence map›Paper›PMID 25208673›Full record

ReviewNeurocritical care2014

International multidisciplinary consensus conference on multimodality monitoring: cerebral metabolism.

Peter Hutchinson, Kristine O'Phelan, Participants in the International Multidisciplinary Consensus Conference on Multimodality Monitoring

Abstract readReviewConsensus Statement
PubMed Publisher
In one paragraph

Review in Neurocritical care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
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  4. Review
  5. Eight rules for the haemodynamic management of traumatic brain-injured patients.European journal of anaesthesiology and intensive care · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Peter HutchinsonDepartment of Clinical Neurosciences, University of Cambridge, Box 167 Addenbrooke's Hospital, Cambridge, CB2 2QQ, UK, kophelan@med.miami.edu.
Kristine O'Phelan
Participants in the International Multidisciplinary Consensus Conference on Multimodality Monitoring
Addenbrooke's Hospital · GBUniversity of Cambridge · GBUniversity of Miami · US

Funding

Department of Health NIHR-RP-R3-12-013Medical Research Council G0001237Medical Research Council G0600986Medical Research Council G0601025Medical Research Council G1002277Medical Research Council G9439390
6 · The paper itself

Abstract

Microdialysis is a powerful technique, which enables the chemistry of the extracellular space to be measured directly. Applying this technique to patients in neurointensive care has increased our understanding of the pathophysiology of traumatic brain injury and spontaneous hemorrhage. In parallel, it is important to determine the place of microdialysis in assisting in the management of patients on an individual intention to treat basis. This is made possible by the availability of analyzers which can measure the concentration of glucose, pyruvate, lactate, and glutamate at the bedside. Samples can then be stored for later analysis of other substrate and metabolites e.g., other amino acids and cytokines. The objective of this paper is to review the fundamental literature pertinent to the clinical application of microdialysis in neurointensive care and to give recommendations on how the technique can be applied to assist in patient management and contribute to outcome. A literature search detected 1,933 publications of which 55 were used for data abstraction and analysis. The role of microdialysis was evaluated in three conditions (traumatic brain injury, subarachnoid hemorrhage, and intracerebral hemorrhage) and recommendations focused on three fundamental areas (relationship to outcome, application of microdialysis to guide therapy, and the ability of microdialysis to predict secondary deterioration).

Indexed as

MicrodialysisNeurophysiological MonitoringBiomarkersBrainBrain InjuriesCritical CareHumansSubarachnoid HemorrhageBiomarkers

Identifiers

PMID25208673
OpenAlexW1969949212

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.