ArticleJournal of studies on alcohol and drugs2014
Acute effects of moderate alcohol on psychomotor, set shifting, and working memory function in older and younger social drinkers.
Article in Journal of studies on alcohol and drugs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of acute alcohol administration on working memory: a systematic review and meta-analysis.Psychopharmacology · 2022Pooled it
- Cognitive training in recently-abstinent individuals with alcohol use disorder improves emotional stroop performance: Evidence from a randomized pilot trial.Drug and alcohol dependence · 2022Trial
- Acute effect of alcohol on working memory updating.Addiction (Abingdon, England) · 2021Trial
- Working Memory Performance Following Acute Alcohol: Replication and Extension of Dose by Age Interactions.Journal of studies on alcohol and drugs · 2019Trial
- Effects of Age and Acute Moderate Alcohol Administration on Neurophysiology During Simulated Driving.Alcoholism, clinical and experimental research · 2016Trial
- Alcohol Doesn't Always Compromise Cognitive Function: Exploring Moderate Doses in Young Adults.Journal of studies on alcohol and drugs · 2015Trial
- The effects of acute alcohol on psychomotor, set-shifting, and working memory performance in older men and women.Alcohol (Fayetteville, N.Y.) · 2015Trial
- Insula under the influence: Alcohol-induced changes in resting state functional connectivity.Alcohol, clinical & experimental research · 2025Article
- A narrative review on alcohol use in women: insight into the telescoping hypothesis from a biopsychosocial perspective.The American journal of drug and alcohol abuse · 2025Review
- Determinants of perceived pain relief from acute alcohol intake in a laboratory setting.Drug and alcohol dependence reports · 2024Article
- Linking alcohol use to Alzheimer's disease: Interactions with aging and APOE along immune pathways.Medical research archives · 2024Article
- Association of cerebellar and pre-motor cortex gray matter density with subjective intoxication and subjective response following acute alcohol intake.Scientific reports · 2023Article
- Pain and alcohol consumption in virtual reality.Experimental and clinical psychopharmacology · 2023Article
- The neuroimmune system - Where aging and excess alcohol intersect.Alcohol (Fayetteville, N.Y.) · 2023Review
- A virtual reality platform for the measurement of drinking topography.Drug and alcohol dependence · 2022Article
- Endorsement of specific alcohol use disorder criterion items changes with age in individuals with persistent alcohol use disorders in 2 generations of the San Diego Prospective Study.Alcoholism, clinical and experimental research · 2021Article
- The Effects of Cannabis Use on Cognitive Function in Healthy Aging: A Systematic Scoping Review.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2021Article
- Acute Tolerance to the Analgesic Effects of Alcohol.Journal of studies on alcohol and drugs · 2021Article
- The impact of emotional face stimuli on working memory performance among men and women with alcohol use disorder.Addictive behaviors · 2021Article
- Sex and Age Effects on Neurobehavioral Toxicity Induced by Binge Alcohol.Brain plasticity (Amsterdam, Netherlands) · 2020Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
unlabelledABSTRACT.
objectiveDespite substantial attention being paid to the health benefits of moderate alcohol intake as a lifestyle, the acute effects of alcohol on psychomotor and working memory function in older adults are poorly understood.
methodThe effects of low to moderate doses of alcohol on neurobehavioral function were investigated in 39 older (55-70 years; 15 men) and 51 younger (25-35 years; 31 men) social drinkers. Subjects received one of three randomly assigned doses (placebo, .04 g/dl, or .065 g/dl target breath alcohol concentration). After beverage consumption, they completed the Trail Making Test Parts A and B and a working memory task requiring participants to determine whether probe stimuli were novel or had been presented in a preceding set of cue stimuli. Efficiency of working memory task performance was derived from accuracy and reaction time measures.
resultsAlcohol was associated with poorer Trail Making Test Part B performance for older subjects. Working memory task results suggested an Age × Dose interaction for performance efficiency, with older but not younger adults demonstrating alcohol-related change. Directionality of change and whether effects on accuracy or reaction time drove the change depended on the novelty of probe stimuli.
conclusionsThis study replicates previous research indicating increased susceptibility of older adults to moderate alcohol-induced psychomotor and set-shifting impairment and suggests such susceptibility extends to working memory performance. Further research using additional tasks and assessing other neuropsychological domains is needed. (J. Stud. Alcohol Drugs, 75, 870-879, 2014).
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