Evidence map›Paper›PMID 25208204›Full record

ArticleJournal of studies on alcohol and drugs2014

Parental alcohol history differentially predicts offspring disorders in distinct subgroups in Israel.

Jacquelyn L Meyers, Dvora Shmulewitz, Jennifer C Elliott, Ronald G Thompson, Efrat Aharonovich, Baruch Spivak, Abraham Weizman, Amos Frisch, Bridget F Grant, Deborah S Hasin

Open access · bronzeAbstract read
In one paragraph

Article in Journal of studies on alcohol and drugs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Jacquelyn L MeyersDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.
Dvora ShmulewitzDepartment of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, New York State Psychiatric Institute, New York, New York.
Jennifer C ElliottDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.
Ronald G ThompsonDepartment of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, New York State Psychiatric Institute, New York, New York.
Efrat AharonovichDepartment of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, New York State Psychiatric Institute, New York, New York.
Baruch SpivakSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Abraham WeizmanSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Felsenstein Medical Research Center, Petah Tikva, Israel, Research Unit, Geha Mental Health Center, Petah Tikva, Israel.
Amos FrischSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Felsenstein Medical Research Center, Petah Tikva, Israel.
Bridget F GrantLaboratory of Epidemiology and Biometry, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland.
Deborah S HasinDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, New York State Psychiatric Institute, New York, New York.
Columbia University · USTel Aviv University · ILNational Institute on Alcohol Abuse and Alcoholism · USNew York Psychoanalytic Society and Institute · USNew York State Psychiatric InstituteRabin Medical Center · IL

Funding

National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) - IIIZIAAA000449 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI GRANT, BRIDGET F · 2009 to 2016
$16.5M
RESEARCH TRAINING PROGRAM IN PSYCHIATRIC EPIDEMIOLOGYT32MH013043 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Katherine M. Keyes · 1985 to 2026
$11.7M
Phenotypes for Drug Abuse:Epidemiologic-Genetic ApproachR01DA018652 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI HASIN, DEBORAH S · 2004 to 2018
$5.3M
Alcohol in Israel: Genetic and Environmental EffectsR01AA013654 · NIAAA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI HASIN, DEBORAH S. · 2003 to 2007
$4.6M
Adverse childhood experiences, personality psychopathology, and alcohol disordersU01AA018111 · NIAAA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI HASIN, DEBORAH S · 2009 to 2013
$3.4M
Epidemiologic Studies of Alcohol Use Disorders (ongoing)K05AA014223 · NIAAA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HASIN, DEBORAH S · 2003 to 2012
$1.5M
Cognition in Cocaine Dependence: Assessment &TherapyK23DA016743 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI AHARONOVICH, EFRAT · 2003 to 2007
$802k
NIAAA NIH HHS K05 AA014223NIAAA NIH HHS K05AA014223NIAAA NIH HHS R01 AA013654NIAAA NIH HHS R01AA013654NIAAA NIH HHS U01 AA018111NIAAA NIH HHS U01AA018111NIDA NIH HHS K23 DA016743NIDA NIH HHS K23DA016743NIDA NIH HHS R01 DA018652NIDA NIH HHS R01DA018652NIMH NIH HHS T32 MH013043NIMH NIH HHS T32MH13043
6 · The paper itself

Abstract

objectiveThe association between alcoholism in parents and related disorders in their offspring is well established in cultures with intermediate/high alcohol consumption, but not in those with low consumption, such as Israel. This study investigated differences in parental transmission of alcohol problems and related psychopathology between immigrants from the former Soviet Union (FSU) to Israel and other Israelis-two Israeli subgroups with differing alcohol consumption behaviors and social norms.

methodA total of 1,347 adults from a household sample were interviewed. Regression analyses were used to examine associations between parental alcohol problems and participant disorders: alcohol, nicotine, and cannabis use disorders (AUD, NUD, CUD); antisocial personality disorder (ASPD); major depressive disorder (MDD); and posttraumatic stress disorder (PTSD). We also examined the associations of parental alcohol problems with participant disorders characterized with two latent factors: externalizing (EXT: AUD, NUD, CUD, ASPD) and internalizing (INT: MDD, PTSD). Differential parental transmission of alcohol problems in FSU (n = 315) and non-FSU (n = 1,032) Israelis was examined with statistical interaction.

resultsAmong emigrants from the FSU, parental alcohol problems predicted AUD, NUD, CUD, ASPD, PTSD, EXT, and INT (mean ratios = 1.38-4.83). In non-FSU Israelis, parental alcohol problems predicted only ASPD and PTSD (mean ratios = 1.08-4.09). Significant interactions were observed for AUD, CUD, PTSD, and EXT; each relationship was stronger in FSU Israelis and null (AUD, CUD, EXT) or less robust (PTSD) in other Israelis.

conclusionsParental alcohol problems were related to substance use and psychiatric disorders differently in FSU and other Israelis, two groups with different alcohol consumption levels and drinking norms. We propose that, in social contexts that vary in the degree to which they constrain alcohol behavior, underlying genetic predispositions may manifest as different disorders.

Indexed as

AdultAlcohol-Related DisordersChild of Impaired ParentsEmigrants and ImmigrantsFemaleHumansIsraelMaleMental DisordersParentsPredictive Value of Tests

Identifiers

PMID25208204
PMCPMC4161705
OpenAlexW2096649002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.