Evidence map›Paper›PMID 25208198›Full record

ReviewJournal of studies on alcohol and drugs2014

Alcohol use disorder clinical course research: informing clinicians' treatment planning now and in the future.

Stephen A Maisto, Megan Kirouac, Katie Witkiewitz

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of studies on alcohol and drugs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03842670 (Neurocognitive and Neurobehavioral Mechanisms of Change Following Psychological), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03842670 nacompletednot on this mapstarted 2018, after this paper: background citation

Neurocognitive and Neurobehavioral Mechanisms of Change Following Psychological

TypeinterventionalSponsorUniversity of New MexicoRan2018 to 2025Enrolled110ConditionsAlcohol Use Disorder, Alcohol Abuse, Alcohol Drinking, Alcohol DependenceArmsCognitive Behavior Therapy, Mindfulness Based Relapse Prevention
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
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  6. Trial
  7. Modeling the dynamics of addiction relapse via the double-well potential system.Journal of psychopathology and clinical science · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Assessment of Alcohol Use in the Natural Environment.Alcoholism, clinical and experimental research · 2019
    Review
  13. Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stephen A MaistoDepartment of Psychology, Syracuse University, Syracuse, New York.
Megan KirouacDepartment of Psychology, University of New Mexico, Albuquerque, New Mexico.
Katie WitkiewitzDepartment of Psychology, University of New Mexico, Albuquerque, New Mexico.

Funding

Alcohol Research Training: Methods & MechanismsT32AA018108 · NIAAA · UNIVERSITY OF NEW MEXICO · PI Katie A Witkiewitz · 2010 to 2026
$5.6M
Precision Medicine and Recovery in a Telehealth Treatment Program for Alcohol Use DisorderR01AA022328 · NIAAA · UNIVERSITY OF NEW MEXICO · PI Katie A Witkiewitz · 2013 to 2026
$3.1M
Research and Mentoring on Alcohol Clinical and Human Laboratory ResearchK05AA016928 · NIAAA · SYRACUSE UNIVERSITY · PI MAISTO, STEPHEN A · 2008 to 2017
$2.1M
Roadmap to Study Mechanisms of Behavior Change in AddictionsU13AA024013 · NIAAA · UNIVERSITY OF NEW MEXICO · PI KARNO, MITCHELL P, WITKIEWITZ, KATIE A · 2015 to 2019
$183k
NIAAA NIH HHS 1R01 AA022328NIAAA NIH HHS K05 AA016928NIAAA NIH HHS R01 AA022328NIAAA NIH HHS T32 AA018108NIAAA NIH HHS U13 AA024013
6 · The paper itself

Abstract

objectiveThe clinical course of alcohol use disorder (AUD) has been widely researched over the past half-century and has been used to advance our understanding of the treatment of AUD. Nevertheless, new directions in AUD clinical course research could enhance its value in informing clinical decision-making in patient-centered treatment of AUD.

methodAn overview, a critical analysis, and a discussion of AUD clinical course research are presented.

resultsThis article discusses three research directions that promote the advancement of the knowledge regarding the clinical course of AUD to better inform clinical decision-making in patient-centered treatment of AUD. Specifically, we hypothesized that (a) real-time data collection of the clinical course of AUD via ecological momentary assessment would help elucidate near real-time associations between risk factors and alcohol use, (b) future research designs should use person-centered and dynamic analyses of alcohol use over time, and (c) adaptive treatment designs would provide personalized and optimized AUD treatment. Consequently, the field will advance the development of clinical decision-making support systems to better inform clinicians and clients in making informed AUD treatment decisions. In addition, such research would advance clinical practice with more attention to theory and expansion of the study of the clinical course of AUD to include areas of life functioning besides alcohol use.

conclusionsThese research directions have the potential to build a scientific knowledge base that could improve our understanding of AUD among individuals with alcohol problems, would allow providers to predict patient outcomes during and after treatment, and would offer practical strategies regarding steps that could ultimately improve the clinical course of AUD.

Indexed as

Clinical ProtocolsPhysiciansAlcohol-Related DisordersBiomedical ResearchForecastingHumans

Identifiers

PMID25208198
PMCPMC4161700

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.