Evidence map›Paper›PMID 25207702›Full record

ArticleClinical pharmacology and therapeutics2014

In vivo metabolic spectroscopy identifies deficits in mitochondrial quality and capacity in aging skeletal muscle.

D J Marcinek, K E Conley

Abstract read
In one paragraph

Article in Clinical pharmacology and therapeutics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

D J Marcinek1] Department of Radiology, University of Washington, Seattle, Washington, USA [2] Department of Bioengineering, University of Washington, Seattle, Washington, USA [3] Department of Pathology, University of Washington, Seattle, Washington, USA.
K E Conley1] Department of Radiology, University of Washington, Seattle, Washington, USA [2] Department of Bioengineering, University of Washington, Seattle, Washington, USA [3] Department of Physiology and Biophysics, University of Washington, Seattle, Washington, USA.

Funding

SPECIFICITY OF OXYGEN DNA DAMAGE AND MUTAGENESISP01AG001751 · NIA · UNIVERSITY OF WASHINGTON · PI RABINOVITCH, PETER S · 1985 to 2021
$29.6M
MR &Optical Diagnosis of Muscle Metabolism and FunctionR01AR041928 · NIAMS · UNIVERSITY OF WASHINGTON · PI CONLEY, KEVIN E · 1993 to 2011
$6.8M
Mitochondrial Dysfunction in Aged MuscleR01AG028455 · NIA · UNIVERSITY OF WASHINGTON · PI MARCINEK, DAVID J. · 2006 to 2010
$2.0M
Translational Center for In Vivo Mitochondrial MedicineRC2AG036606 · NIA · UNIVERSITY OF WASHINGTON · PI CONLEY, KEVIN E, MARCINEK, DAVID J. · 2009 to 2010
$1.5M
RESPIRATION AND GLYCOLYSIS--INTEGRATION IN ACTIVE MUSCLER01AR045184 · NIAMS · UNIVERSITY OF WASHINGTON · PI CONLEY, KEVIN E · 1998 to 2002
$872k
Study of Energy and AgingRC2AG036594 · NIA · CALIFORNIA PACIFIC MED CTR RES INSTITUTE · PI CUMMINGS, STEVEN RON · 2009 to 2009
$856k
SS peptides: improve mitochondrial and skeletal muscle function with ageR21AG042637 · NIA · UNIVERSITY OF WASHINGTON · PI MARCINEK, DAVID J. · 2012 to 2013
$480k
NIAMS NIH HHS AR41928NIAMS NIH HHS AR45184NIAMS NIH HHS R01 AR041928NIA NIH HHS AG001751NIA NIH HHS AG028455NIA NIH HHS AG042637NIA NIH HHS P01 AG001751NIA NIH HHS R01 AG028455NIA NIH HHS R21 AG042637NIA NIH HHS RC2 AG036594NIA NIH HHS RC2AG036594NIA NIH HHS RC2 AG036606NIA NIH HHS RC2AG036606PHS HHS AGAR10853
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgingAnimalsEnergy MetabolismHumansMiceMitochondriaMitochondrial DiseasesMuscle, SkeletalOxygen ConsumptionSpectrum Analysis

Identifiers

PMID25207702
PMCPMC4707046

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.