Evidence map›Paper›PMID 25206937›Full record

ReviewThe EPMA journal2014

Induced urinary crystal formation as an analytical strategy for the prediction and monitoring of urolithiasis and other metabolism-related disorders.

Norbert Laube, Wolfgang Berg, Falk Bernsmann, Sascha Gravius, Florian Klein, Stefan Latz, Dirk von Mallek, Tadeusz Porowski, Thomas Randau, Anna Wasilewska and 1 more

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The EPMA journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Norbert LaubeDeutsches Harnsteinzentrum, Urologisches Zentrum Bonn Friedensplatz, Friedensplatz 16, Bonn 53111, Germany ; NTTF Coatings GmbH, Maarweg 32, Rheinbreitbach 53619, Germany.
Wolfgang BergClinic and Policlinic of Urology, Friedrich Schiller University of Jena, Lessingstraße 1, Jena 07743, Germany.
Falk BernsmannNTTF Coatings GmbH, Maarweg 32, Rheinbreitbach 53619, Germany.
Sascha GraviusClinic for Orthopaedics and Trauma Surgery, Friedrich-Wilhelms-Universität Bonn, Sigmund-Freud-Straße 25, Bonn 53127, Germany.
Florian KleinFH Aachen, Campus Jülich, FB Medizintechnik und Technomathematik, Heinrich-Mußmann-Straße 1, Jülich 52428, Germany.
Stefan LatzClinic and Policlinic of Urology and Pediatric Urology, Friedrich-Wilhelms-Universität Bonn, Sigmund-Freud-Straße 25, Bonn 53127, Germany.
Dirk von MallekDepartment of Research, Federal Institute for Drugs and Medical Devices (BfArM), Kurt-Georg-Kiesinger-Allee 3, Bonn, 53175, Germany.
Tadeusz PorowskiDepartment of Pediatrics and Nephrology, Medical University of Białystok ul, Waszyngtona 17, Białystok 15-546, Poland.
Thomas RandauClinic for Orthopaedics and Trauma Surgery, Friedrich-Wilhelms-Universität Bonn, Sigmund-Freud-Straße 25, Bonn 53127, Germany.
Anna WasilewskaDepartment of Pediatrics and Nephrology, Medical University of Białystok ul, Waszyngtona 17, Białystok 15-546, Poland.
Christian FisangClinic and Policlinic of Urology and Pediatric Urology, Friedrich-Wilhelms-Universität Bonn, Sigmund-Freud-Straße 25, Bonn 53127, Germany.
University of Bonn · DEMedical University of Białystok · PLFederal Institute for Drugs and Medical Devices · DEFH Aachen · DEFriedrich Schiller University Jena · DEROWO Coating (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crystal formation reflects the entire composition of the surrounding solution. In case of urolithiasis, induced crystal formation in native urine has led to the development of the Bonn-Risk-Index (BRI), a valuable tool to quantify an individual's risk of calcium oxalate urolithiasis. If the progression of a disease is associated with characteristic changes in the activities of urinary components, this leads to an altered urinary crystallisation capacity. Therefore, the results of induced urinary crystal formation can be used to detect and monitor any disease linked to the altered urinary composition. Since crystal formation inherently takes into account the entire urinary composition, the influence of the disease on individual urinary parameters does not have to be known in order to monitor the consequent pathologic alterations. In this paper, we review the background of urinary crystal formation analysis and describe its established application in urolithiasis monitoring as well as potential further fields of clinical application.

Indexed as

Bonn-Risk-IndexDisease/treatment monitoringMeno-/andropauseMetabolic diseasesNephropathiesPredictive preventive personalised medicineUrinary crystal formation

Identifiers

PMID25206937
PMCPMC4150547
OpenAlexW2171415779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.