Evidence map›Paper›PMID 25206907›Full record

ArticleNeural regeneration research2014

Virtual reality interface devices in the reorganization of neural networks in the brain of patients with neurological diseases.

Valeska Gatica-Rojas, Guillermo Méndez-Rebolledo

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neural regeneration research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07722169 (Home-based Virtual Reality Cognitive Training as an add-on to Telerehabilitation in Alzheimer's Disease), which is not on this map. Cited by 26 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07722169 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Home-based Virtual Reality Cognitive Training as an add-on to Telerehabilitation in Alzheimer's Disease: Validation of a Protocol to Slow Down Cognitive Decline and Reduce Caregivers' Burden

TypeinterventionalSponsorIRCCS San RaffaeleRan2026 to 2029Enrolled48ConditionsAlzheimerArmsOnline cognitive telerehabilitation, VRRS tablet
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. NintendoInternational journal of environmental research and public health · 2022
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  15. Home-Based Functional Electrical Stimulation-Assisted Hand Therapy Video Games for Children With Hemiplegia: Development and Proof-of-Concept.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Valeska Gatica-RojasLaboratory of Human Motor Control, Faculty of Health Sciences, University of Talca, Talca, Chile.
Guillermo Méndez-RebolledoLaboratory of Human Motor Control, School of Kinesiology, Faculty of Health Sciences, University of Talca, Talca, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two key characteristics of all virtual reality applications are interaction and immersion. Systemic interaction is achieved through a variety of multisensory channels (hearing, sight, touch, and smell), permitting the user to interact with the virtual world in real time. Immersion is the degree to which a person can feel wrapped in the virtual world through a defined interface. Virtual reality interface devices such as the Nintendo® Wii and its peripheral nunchuks-balance board, head mounted displays and joystick allow interaction and immersion in unreal environments created from computer software. Virtual environments are highly interactive, generating great activation of visual, vestibular and proprioceptive systems during the execution of a video game. In addition, they are entertaining and safe for the user. Recently, incorporating therapeutic purposes in virtual reality interface devices has allowed them to be used for the rehabilitation of neurological patients, e.g., balance training in older adults and dynamic stability in healthy participants. The improvements observed in neurological diseases (chronic stroke and cerebral palsy) have been shown by changes in the reorganization of neural networks in patients' brain, along with better hand function and other skills, contributing to their quality of life. The data generated by such studies could substantially contribute to physical rehabilitation strategies.

Indexed as

agedcerebral palsynerve regenerationneural regenerationnintendo wii balance boardpostural balancerehabilitationreviewstrokevirtual environmentvirtual realityvirtual reality exposure therapy

Identifiers

PMID25206907
PMCPMC4146258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.