Evidence map›Paper›PMID 25206786›Full record

ReviewNeural regeneration research2014

Diffuse axonal injury after traumatic cerebral microbleeds: an evaluation of imaging techniques.

Jun Liu, Zhifeng Kou, Yongquan Tian

Open access · goldAbstract readReview
In one paragraph

Review in Neural regeneration research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 88 citations in OpenAlex.

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  20. Mechanisms of Blood-Brain Barrier Dysfunction in Traumatic Brain Injury.International journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Jun LiuDepartment of Radiology, Second Xiangya Hospital, Central South University, Changsha, Hunan Province, China ; Department of Biomedical Engineering and Radiology, School of Medicine, Wayne State University, 3990 John R St, Detroit, MI, USA ; School of Public Administration, Central South University, Changsha, Hunan Province, China.
Zhifeng KouDepartment of Biomedical Engineering and Radiology, School of Medicine, Wayne State University, 3990 John R St, Detroit, MI, USA.
Yongquan TianSchool of Public Administration, Central South University, Changsha, Hunan Province, China.
Central South University · CNWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous neuropathological studies regarding traumatic brain injury have primarily focused on changes in large structures, for example, the clinical prognosis after cerebral contusion, intracerebral hematoma, and epidural and subdural hematoma. In fact, many smaller injuries can also lead to severe neurological disorders. For example, cerebral microbleeds result in the dysfunction of adjacent neurons and the disassociation between cortex and subcortical structures. These tiny changes cannot be adequately visualized on CT or conventional MRI. In contrast, gradient echo sequence-based susceptibility-weighted imaging is very sensitive to blood metabolites and microbleeds, and can be used to evaluate traumatic cerebral microbleeds with high sensitivity and accuracy. Cerebral microbleed can be considered as an important imaging marker for diffuse axonal injury with potential relevance for prognosis. For this reason, based on experimental and clinical studies, this study reviews the role of imaging data showing traumatic cerebral microbleeds in the evaluation of cerebral neuronal injury and neurofunctional loss.

Indexed as

cerebral microbleedsdiffuse axonal injurygradient-recalled-echonerve regenerationneural regenerationneuroimagingreviewsusceptibility weighted imagingtraumatic brain injury

Identifiers

PMID25206786
PMCPMC4146289
OpenAlexW2082259327

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.