Evidence map›Paper›PMID 25206698›Full record

ArticleNeural regeneration research2013

Microelectronic neural bridging of toad nerves to restore leg function.

Xiaoyan Shen, Zhigong Wang, Xiaoying Lv, Zonghao Huang

Open access · greenAbstract read
In one paragraph

Article in Neural regeneration research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xiaoyan ShenSchool of Electronic Information, Nantong University, Nantong 226007, Jiangsu Province, China ; Institute of RF- & OE-ICs, Southeast University, Nanjing 210096, Jiangsu Province, China.
Zhigong WangInstitute of RF- & OE-ICs, Southeast University, Nanjing 210096, Jiangsu Province, China.
Xiaoying LvState Key Laboratory of Bioelectronics, Southeast University, Nanjing 210096, Jiangsu Province, China.
Zonghao HuangInstitute of RF- & OE-ICs, Southeast University, Nanjing 210096, Jiangsu Province, China.
Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study used a microelectronic neural bridge comprised of electrode arrays for neural signal detection, functional electrical stimulation, and a microelectronic circuit including signal amplifying, processing, and functional electrical stimulation to bridge two separate nerves, and to restore the lost function of one nerve. The left leg of one spinal toad was subjected to external mechanical stimulation and functional electrical stimulation driving. The function of the left leg of one spinal toad was regenerated to the corresponding leg of another spinal toad using a microelectronic neural bridge. Oscilloscope tracings showed that the electromyographic signals from controlled spinal toads were generated by neural signals that controlled the spinal toad, and there was a delay between signals. This study demonstrates that microelectronic neural bridging can be used to restore neural function between different injured nerves.

Indexed as

basic researchcoherence functionelectromyographic signalgrants-supported papermicroelectronic neural bridgenerve injuryneural regenerationneuroregenerationphotographs-containing paperspinal reflex arcspinal toad

Identifiers

PMID25206698
PMCPMC4146052
OpenAlexW1433995915

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.