Evidence map›Paper›PMID 25206602›Full record

ArticleNeural regeneration research2013

Pre-moxibustion and moxibustion prevent Alzheimer's disease.

Yanjun Du, Ruolan Liu, Guojie Sun, Peiyan Meng, Jie Song

Open access · greenAbstract read
In one paragraph

Article in Neural regeneration research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Effect of moxibustion on expression profile of miRNAs in Tripterygium glycoside-induced decreased ovarian reserve.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024
    Article
  3. Review
  4. Article
  5. Review
  6. Effect of Moxibustion on Testosterone Secretion and Apoptosis of Spermatogenic Cells in Aging Rats.Evidence-based complementary and alternative medicine : eCAM · 2019
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yanjun DuCollege of Acupuncture and Moxibustion, Hubei University of Chinese Medicine, Wuhan 430061, Hubei Province, China.
Ruolan LiuDepartment of Rehabilitation, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei Province, China.
Guojie SunCollege of Acupuncture and Moxibustion, Hubei University of Chinese Medicine, Wuhan 430061, Hubei Province, China.
Peiyan MengCollege of Acupuncture and Moxibustion, Hubei University of Chinese Medicine, Wuhan 430061, Hubei Province, China.
Jie SongCollege of Acupuncture and Moxibustion, Hubei University of Chinese Medicine, Wuhan 430061, Hubei Province, China.
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Alzheimer's disease model in Wistar rats was established by injection of amyloid β-peptide (Aβ1-42) into the hippocampal CA1 region. Rats were treated with suspended moxibustion on Baihui (GV20) and Shenshu (BL23) acupoints. Prior to and post Aβ1-42 exposure. Results showed no evidence of apoptosis in hippocampal neurons, a significantly reduced apoptosis rate of neurons and improved learning and memory abilities were observed in the Alzheimer's disease model. In particular, moxibustion prior to Aβ1-42 exposure was more effective than moxibustion after Aβ1-42 exposure in protecting the neuronal structure and lowering the apoptosis rate. Our findings indicate that a combination of preventive and therapeutic moxibustion has a beneficial effect for the prevention of Alzheimer's disease development.

Indexed as

acupunctureAlzheimer's diseaseapoptosisdementiagrants-supported paperhippocampusmoxibustionneural regenerationneuroregeneration

Identifiers

PMID25206602
PMCPMC4146019
OpenAlexW57869177

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.