Evidence map›Paper›PMID 25206598›Full record

ArticleNeural regeneration research2013

Back propagation artificial neural network for community Alzheimer's disease screening in China.

Jun Tang, Lei Wu, Helang Huang, Jiang Feng, Yefeng Yuan, Yueping Zhou, Peng Huang, Yan Xu, Chao Yu

Abstract read
In one paragraph

Article in Neural regeneration research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jun TangDepartment of Epidemiology, Public Health Institute, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Lei WuDepartment of Epidemiology, Public Health Institute, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Helang HuangDepartment of Epidemiology, Public Health Institute, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Jiang FengDepartment of Chemistry, Public Health Institute, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Yefeng YuanDepartment of Psychosomatic Medicine, First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China.
Yueping ZhouDepartment of Epidemiology, Public Health Institute, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Peng HuangDepartment of Epidemiology, Public Health Institute, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Yan XuDepartment of Epidemiology, Public Health Institute, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Chao YuDepartment of Epidemiology, Public Health Institute, Nanchang University, Nanchang 330006, Jiangxi Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease patients diagnosed with the Chinese Classification of Mental Disorders diagnostic criteria were selected from the community through on-site sampling. Levels of macro and trace elements were measured in blood samples using an atomic absorption method, and neurotransmitters were measured using a radioimmunoassay method. SPSS 13.0 was used to establish a database, and a back propagation artificial neural network for Alzheimer's disease prediction was simulated using Clementine 12.0 software. With scores of activities of daily living, creatinine, 5-hydroxytryptamine, age, dopamine and aluminum as input variables, the results revealed that the area under the curve in our back propagation artificial neural network was 0.929 (95% confidence interval: 0.868-0.968), sensitivity was 90.00%, specificity was 95.00%, and accuracy was 92.50%. The findings indicated that the results of back propagation artificial neural network established based on the above six variables were satisfactory for screening and diagnosis of Alzheimer's disease in patients selected from the community.

Indexed as

Alzheimer's diseaseartificial neural networkclinical practicecommunitygrant-supported papermathematical modelneural regenerationneuroregenerationneurotransmitterstrace elements

Identifiers

PMID25206598
PMCPMC4107524

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.