Evidence map›Paper›PMID 25206525›Full record

ArticleNeural regeneration research2013

Which form of collagen is suitable for nerve cell culture?

Mohsen Fathi Najafi, Saber Zahri, Fatemeh Vahedi, Leila Esmaililian Toosi, Nazila Ariaee

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neural regeneration research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mohsen Fathi NajafiRazi Vaccine and Serum Research Institute, Mashhad, Iran.
Saber ZahriDepartamnt of Biology, University of Mohaghegh Ardebili, Ardebil, Iran.
Fatemeh VahediRazi Vaccine and Serum Research Institute, Mashhad, Iran.
Leila Esmaililian ToosiInflammation and Inflammatory Diseases Research Center, Mashhad University of Medical Science, Mashhad, Iran.
Nazila AriaeeDepartamnt of Biology, University of Mohaghegh Ardebili, Ardebil, Iran ; Inflammation and Inflammatory Diseases Research Center, Mashhad University of Medical Science, Mashhad, Iran.
Razi Vaccine and Serum Research Institute · IRMashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we investigated the effects of hydrolyzed and non-hydrolyzed collagen and two-dimensional and three-dimensional collagen matrices on cell survival, attachment and neurite outgrowth of primary cultured nerve cells using 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) colorimetric assay and inverted microscopy. Hydrolyzed collagen facilitated nerve cell survival and neurite outgrowth, but it had no obvious influences on cell attachment. In contrast, non-hydrolyzed two-dimensional collagen matrix had no obvious effects on neurite outgrowth. These findings suggest that hydrolyzed collagen is an ideal nerve cell culture media.

Indexed as

cell attachmentcollagengrants-supported papergrowthmatrixnerve cellsneural regenerationneuroregenerationprimary culturesurvival

Identifiers

PMID25206525
PMCPMC4146121
OpenAlexW1509750698

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.