Evidence map›Paper›PMID 25206458›Full record

ArticleNeural regeneration research2013

Health-related quality of life in Parkinson's disease patients in northeastern Sicily, Italy: (An ecological perspective).

Letteria Spadaro, Lilla Bonanno, Giuseppe Di Lorenzo, Placido Bramanti, Silvia Marino

Abstract read
In one paragraph

Article in Neural regeneration research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Letteria SpadaroIstituto di Ricovero e Cura a Carattere Scientifico Centro Neurolesi "Bonino Pulejo" Via Provinciale Palermo, C.da Casazza 98124 Messina, Italy.
Lilla BonannoIstituto di Ricovero e Cura a Carattere Scientifico Centro Neurolesi "Bonino Pulejo" Via Provinciale Palermo, C.da Casazza 98124 Messina, Italy.
Giuseppe Di LorenzoIstituto di Ricovero e Cura a Carattere Scientifico Centro Neurolesi "Bonino Pulejo" Via Provinciale Palermo, C.da Casazza 98124 Messina, Italy.
Placido BramantiIstituto di Ricovero e Cura a Carattere Scientifico Centro Neurolesi "Bonino Pulejo" Via Provinciale Palermo, C.da Casazza 98124 Messina, Italy.
Silvia MarinoIstituto di Ricovero e Cura a Carattere Scientifico Centro Neurolesi "Bonino Pulejo" Via Provinciale Palermo, C.da Casazza 98124 Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease has a negative impact on health-related quality of life in Parkinson's disease patients. Depression, cognitive impairment, coping strategies, dyskinesia, gait disorders and complications of dopaminergic drugs are the variables that most affect health-related quality of life. The ecological model of human development focuses attention on both individual and social environmental factors as targets for health interventions. From this perspective, the aim of this cross-sectional survey was to evaluate the influence of gender, family size and perceived autonomy on health-related quality of life in Parkinson's disease patients in northeastern Sicily, Italy. Ninety Parkinson's disease patients, attending the Movement Disorders Clinic at IRCCS Centro Neurolesi "Bonino-Pulejo" (Messina), were consecutively enrolled. The Unified Parkinson Disease Rating Scale motor subscale (UPDRS-III) scores, the Parkinson Disease Questionnaire-39 Item scores (as a disease-specific measure of health-related quality of life), scores on the Short Form (36) Health Survey Questionnaire (as a generic measure), and answers to a brief checklist were recorded. A total of 85 Parkinson's disease patients (49% males and 51% females; mean age 70.8 ± 8.6 years; mean UPDRS-III 24.15 ± 6.55; mean disease duration 5.52 ± 4.65 years) completed the booklet of questionnaires. In the multivariate regression analysis, we included clinical and social variables as independent predictors of health-related quality of life. Our results suggest a potential compounding effect of ecological intrapersonal and interpersonal levels on health-related quality of life outcomes. Gender, self-evaluated autonomy and family size significantly impacted health-related quality of life. If quality of life is used as an indicator of treatment outcomes, an ecological perspective of the case history will be important to disclose relevant prognostic information and trigger personalized health care interventions.

Indexed as

caregiverecological modelgrants-supported paperhealth-related quality of lifeneural regenerationneurodegenerative diseaseParkinson’s diseaseParkinson’s Disease Questionnaire-39 Itemssocial variablesthe Unified Parkinson Disease Rating Scale motor subscales

Identifiers

PMID25206458
PMCPMC4145963

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.