Evidence map›Paper›PMID 25206390›Full record

ArticleNeural regeneration research2013

Amniotic membrane covering for facial nerve repair.

Murat Karaman, Arzu Tuncel, Shahrouz Sheidaei, Mehmet Güney Senol, Murat Hakan Karabulut, Ildem Deveci, Nihan Karaman

Open access · greenAbstract read
In one paragraph

Article in Neural regeneration research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Murat KaramanDepartment of Otorhinolaryngology, Ümraniye State Hospital for Research and Training, İstanbul, Turkey.
Arzu TuncelDepartment of Otorhinolaryngology, Haydarpaşa Numune State Hospital for Research and Training, İstanbul, Turkey.
Shahrouz SheidaeiDepartment of Otorhinolaryngology, Haydarpaşa Numune State Hospital for Research and Training, İstanbul, Turkey.
Mehmet Güney SenolDepartment of Neurology, GATA Haydarpaşa State Hospital for Research and Training, İstanbul, Turkey.
Murat Hakan KarabulutDepartment of Otorhinolaryngology, Ümraniye State Hospital for Research and Training, İstanbul, Turkey.
Ildem DeveciDepartment of Otorhinolaryngology, Ümraniye State Hospital for Research and Training, İstanbul, Turkey.
Nihan KaramanDepartment of Dentistry, Turkish Military Services, İstanbul, Turkey.
Ümraniye Eğitim ve Araştırma Hastanesi · TRHaydarpaşa Numune Eğitim ve Araştırma Hastanesi · TRGATA Haydarpaşa Eğitim Hastanesi · TRTurkish Military Academy · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amniotic membranes have been widely used in ophthalmology and skin injury repair because of their anti-inflammatory properties. In this study, we measured therapeutic efficacy and determined if amniotic membranes could be used for facial nerve repair. The facial nerves of eight rats were dissected and end-to-end anastomosis was performed. Amniotic membranes were covered on the anastomosis sites in four rats. Electromyography results showed that, at the end of the 3(rd) and 8(th) weeks after amniotic membrane covering, the latency values of the facial nerves covered by amniotic membranes were significantly shortened and the amplitude values were significantly increased. Compared with simple facial nerve anastomosis, after histopathological examination, facial nerve anastomosed with amniotic membrane showed better continuity, milder inflammatory reactions, and more satisfactory nerve conduction. These findings suggest that amniotic membrane covering has great potential in facial nerve repair.

Indexed as

amniotic membraneamplitudeelectromyographyfacial nerve injurylatencynerve anastomosisneural regenerationneuroregenerationperipheral nerve injurytissue engineering

Identifiers

PMID25206390
PMCPMC4145884
OpenAlexW2252326164

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.