Evidence map›Paper›PMID 25206383›Full record

ArticleNeural regeneration research2013

Transcription factor changes following long term cerebral ischemia/reperfusion injury.

Hongbo Zhang, Weijuan Gao, Tao Qian, Jinglong Tang, Jun Li

Open access · greenAbstract read
In one paragraph

Article in Neural regeneration research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hongbo ZhangDepartment of Pathophysiology, Chengde Medical College, Chengde 067000, Hebei Province, China.
Weijuan GaoHebei Chemical and Pharmaceutical College, Shijiazhuang 050026, Hebei Province, China.
Tao QianHebei Provincial People's Hospital, Shijiazhuang 050051, Hebei Province, China.
Jinglong TangDepartment of Pathophysiology, Chengde Medical College, Chengde 067000, Hebei Province, China.
Jun LiDepartment of Pathophysiology, Chengde Medical College, Chengde 067000, Hebei Province, China.
Affiliated Hospital of Chengde Medical College · CNHebei Chemical and Pharmaceutical College · CNHospital of Hebei Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study established a rat model of cerebral ischemia/reperfusion injury using four-vessel occlusion and found that hippocampal CA1 neuronal morphology was damaged, and that there were reductions in hippocampal neuron number and DNA-binding activity of cAMP response element binding protein and CCAAT/enhancer binding protein, accompanied by decreased learning and memory ability. These findings indicate that decline of hippocampal cAMP response element binding protein and CCAAT/enhancer binding protein DNA-binding activities may contribute to neuronal injury and learning and memory ability reduction induced by cerebral ischemia/reperfusion injury.

Indexed as

brainbrain injurycAMP response element binding proteinCCAAT/enhancer binding proteincerebral ischemia/reperfusionDNA-binding activitygrants-supported paperhippocampusneural regenerationneuroregeneration

Identifiers

PMID25206383
PMCPMC4145920
OpenAlexW1494473624

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.