ArticleFrontiers in genetics2014
Assessing when chromosomal rearrangements affect the dynamics of speciation: implications from computer simulations.
Article in Frontiers in genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Chromosomal Inversion Associated With Diet Differences in Common Quails Sharing Wintering Grounds.Ecology and evolution · 2025Article
- A macroevolutionary role for chromosomal fusion and fission inScience advances · 2024Article
- Review
- Decoding the fibromelanosis locus complex chromosomal rearrangement of black-bone chicken: genetic differentiation, selective sweeps and protein-coding changes in Kadaknath chicken.Frontiers in genetics · 2023Article
- Review
- Inversion invasions: when the genetic basis of local adaptation is concentrated within inversions in the face of gene flow.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Positive selection alone is sufficient for whole genome differentiation at the early stage of speciation process in the fall armyworm.BMC evolutionary biology · 2020Article
- Can the genomics of ecological speciation be predicted across the divergence continuum from host races to species? A case study inPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- The role of copy-number variation in the reinforcement of sexual isolation between the two European subspecies of the house mouse.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- The Chromosome-Level Genome Assembly of European Grayling Reveals Aspects of a Unique Genome Evolution Process Within Salmonids.G3 (Bethesda, Md.) · 2019Article
- Disentangling structural genomic and behavioural barriers in a sea of connectivity.Molecular ecology · 2019Article
- Article
- Article
- No evidence for maintenance of a sympatricEvolution letters · 2017Article
- Making sense of genomic islands of differentiation in light of speciation.Nature reviews. Genetics · 2017Review
- Three chromosomal rearrangements promote genomic divergence between migratory and stationary ecotypes of Atlantic cod.Scientific reports · 2016Article
- Can the experimental evolution programme help us elucidate the genetic basis of adaptation in nature?Molecular ecology · 2016Review
- Maintenance of species boundaries in a Neotropical radiation of Begonia.Molecular ecology · 2015Article
- Ecological and evolutionary implications of genomic structural variations.Frontiers in genetics · 2014Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many hypotheses have been put forth to explain the origin and spread of inversions, and their significance for speciation. Several recent genic models have proposed that inversions promote speciation with gene flow due to the adaptive significance of the genes contained within them and because of the effects inversions have on suppressing recombination. However, the consequences of inversions for the dynamics of genome wide divergence across the speciation continuum remain unclear, an issue we examine here. We review a framework for the genomics of speciation involving the congealing of the genome into alternate adaptive states representing species ("genome wide congealing"). We then place inversions in this context as examples of how genetic hitchhiking can potentially hasten genome wide congealing. Specifically, we use simulation models to (i) examine the conditions under which inversions may speed genome congealing and (ii) quantify predicted magnitudes of these effects. Effects of inversions on promoting speciation were most common and pronounced when inversions were initially fixed between populations before secondary contact and adaptation involved many genes with small fitness effects. Further work is required on the role of underdominance and epistasis between a few loci of major effect within inversions. The results highlight five important aspects of the roles of inversions in speciation: (i) the geographic context of the origins and spread of inversions, (ii) the conditions under which inversions can facilitate divergence, (iii) the magnitude of that facilitation, (iv) the extent to which the buildup of divergence is likely to be biased within vs. outside of inversions, and (v) the dynamics of the appearance and disappearance of exceptional divergence within inversions. We conclude by discussing the empirical challenges in showing that inversions play a central role in facilitating speciation with gene flow.
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