ArticleFrontiers in genetics2014
A bioinformatics workflow for detecting signatures of selection in genomic data.
Article in Frontiers in genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Integrative Genomic and Transcriptomic Insights into High-Altitude Adaptation in Changthangi Goats.Applied biochemistry and biotechnology · 2026Article
- Genomic analysis reveals population structure and selection signatures in plateau dairy cattle.BMC genomics · 2025Article
- Genome-Wide Scans for Selection Signatures in Haimen Goats Reveal Candidate Genes Associated with Growth Traits.Biology · 2025Article
- Shared rare genetic variants in multiplex autism families suggest a social memory gene under selection.Scientific reports · 2025Article
- Landscape genomics reveals regions associated with adaptive phenotypic and genetic variation in Ethiopian indigenous chickens.BMC genomics · 2024Article
- RNA-Seq based selection signature analysis for identifying genomic footprints associated with the fat-tail phenotype in sheep.Frontiers in veterinary science · 2024Article
- Pan-genome of Citrullus genus highlights the extent of presence/absence variation during domestication and selection.BMC genomics · 2023Article
- Genome-wide association study of drought tolerance traits in sugar beet germplasms at the seedling stage.Frontiers in genetics · 2023Article
- Article
- An Evolutionary Insight Into the Heterogeneous Severity Pattern of the SARS-CoV-2 Infection.Frontiers in genetics · 2022Article
- Genome-wide scans for signatures of selection in Mangalarga Marchador horses using high-throughput SNP genotyping.BMC genomics · 2021Article
- Article
- Landscape genomics and selection signatures of local adaptation of Eritrean indigenous cattle along environmental gradients.Tropical animal health and production · 2021Article
- Analysis of selection signatures on the Z chromosome of bidirectional selection broiler lines for the assessment of abdominal fat content.BMC genomic data · 2021Article
- Genetic diversity and population structure of advanced clones selected over forty years by a potato breeding program in the USA.Scientific reports · 2021Article
- An Experimental Test of Adaptive Introgression in Locally Adapted Populations of Splash Pool Copepods.Molecular biology and evolution · 2021Article
- Article
- Genetic Landscape of Rare Autoinflammatory Disease Variants in Qatar and Middle Eastern Populations Through the Integration of Whole-Genome and Exome Datasets.Frontiers in genetics · 2021Article
- Evolutionary selection of alleles in the melanophilin gene that impacts on prostate organ function and cancer risk.Evolution, medicine, and public health · 2021Article
- Selective sweep analysis reveals extensive parallel selection traits between large white and Duroc pigs.Evolutionary applications · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The detection of "signatures of selection" is now possible on a genome-wide scale in many plant and animal species, and can be performed in a population-specific manner due to the wealth of per-population genome-wide genotype data that is available. With genomic regions that exhibit evidence of having been under selection shown to also be enriched for genes associated with biologically important traits, detection of evidence of selective pressure is emerging as an additional approach for identifying novel gene-trait associations. While high-density genotype data is now relatively easy to obtain, for many researchers it is not immediately obvious how to go about identifying signatures of selection in these data sets. Here we describe a basic workflow, constructed from open source tools, for detecting and examining evidence of selection in genomic data. Code to install and implement the pipeline components, and instructions to run a basic analysis using the workflow described here, can be downloaded from our public GitHub repository: http://www.github.com/smilefreak/selectionTools/
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