ReviewFrontiers in psychology2014
Cardiac autonomic imbalance by social stress in rodents: understanding putative biomarkers.
Review in Frontiers in psychology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Healthcare professionals' perceptions of system preparedness during public health emergencies: a path analysis of mental health impacts.Frontiers in public health · 2025Article
- Pro-arrhythmic role of adrenergic spatial densities in the human atria: An in-silico study.PloS one · 2023Article
- Anterior cingulate cortex, but not amygdala, modulates the anxiogenesis induced by living with conspecifics subjected to chronic restraint stress in male mice.Frontiers in behavioral neuroscience · 2022Article
- Hypoactive Thalamic Crh+ Cells in a Female Mouse Model of Alcohol Drinking After Social Trauma.Biological psychiatry · 2021Article
- The Moderating Role of Coping Style on Chronic Stress Exposure and Cardiovascular Reactivity Among African American Emerging Adults.Prevention science : the official journal of the Society for Prevention Research · 2021Article
- Prefrontal Cortex Regulates Chronic Stress-Induced Cardiovascular Susceptibility.Journal of the American Heart Association · 2019Article
- The Effects of Submaximal and Maximal Exercise on Heart Rate Variability.International journal of exercise science · 2019Article
- Novice Meditators of an Easily Learnable Audible Mantram Sound Self-Induce an Increase in Vagal Tone During Short-term Practice: A Preliminary Study.Integrative medicine (Encinitas, Calif.) · 2018Article
- Individual differences in the locus coeruleus-norepinephrine system: Relevance to stress-induced cardiovascular vulnerability.Physiology & behavior · 2017Review
- The brain norepinephrine system, stress and cardiovascular vulnerability.Neuroscience and biobehavioral reviews · 2017Review
- Impaired heart rate variability in cervical dystonia is associated to depression.Journal of neural transmission (Vienna, Austria : 1996) · 2017Article
- Opinion: "Heart Rate Variability, Health and Well-Being: A Systems Perspective" Research Topic.Frontiers in public health · 2017Article
- Atrial Fibrillation: The Science behind Its Defiance.Aging and disease · 2016Review
- A Method for Psychosocial Stress-Induced Reinstatement of Cocaine Seeking in Rats.Biological psychiatry · 2016Article
- Acute Stress Decreases but Chronic Stress Increases Myocardial Sensitivity to Ischemic Injury in Rodents.Frontiers in psychiatry · 2016Review
- Treating the mind to improve the heart: the summon to cardiac psychology.Frontiers in psychology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Exposure to stress or traumatic events can lead to the development of depression and anxiety disorders. In addition to the debilitating consequences on mental health, patients with psychiatric disorders also suffer from autonomic imbalance, making them susceptible to a variety of medical disorders. Emerging evidence utilizing spectral analysis of heart rate variability (HRV), a reliable non-invasive measure of cardiovascular autonomic regulation, indicates that patients with depression and various anxiety disorders (i.e., panic, social, generalized anxiety disorders, and post traumatic stress disorder) are characterized by decreased HRV. Social stressors in rodents are ethologically relevant experimental stressors that recapitulate many of the dysfunctional behavioral and physiological changes that occur in psychological disorders. In this review, evidence from clinical studies and preclinical stress models identify putative biomarkers capable of precipitating the comorbidity between disorders of the mind and autonomic dysfunction. Specifically, the role of corticotropin releasing factor, neuropeptide Y and inflammation are investigated. The impetus for this review is to highlight stress-related biomarkers that may prove critical in the development of autonomic imbalance in stress -related psychiatric disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.