Evidence map›Paper›PMID 25206272›Full record

ReviewWorld journal of gastroenterology2014

Bacteriophages and their applications in the diagnosis and treatment of hepatitis B virus infection.

Babak Bakhshinejad, Majid Sadeghizadeh

Open access · bronzeAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Gut microbiome and liver diseases.Fundamental research · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Therapeutic potential of phages in autoimmune liver diseases.Clinical and experimental immunology · 2018
    Review
  13. Article
  14. Article
  15. Review
  16. [Research advances in necessity of antiviral therapy for chronic hepatitis B virus carriers].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2016
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Babak BakhshinejadBabak Bakhshinejad, Majid Sadeghizadeh, Department of Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran 14115-111, Iran.
Majid SadeghizadehBabak Bakhshinejad, Majid Sadeghizadeh, Department of Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran 14115-111, Iran.
Tarbiat Modares University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B virus (HBV) infection is a major global health challenge leading to serious disorders such as cirrhosis and hepatocellular carcinoma. Currently, there exist various diagnostic and therapeutic approaches for HBV infection. However, prevalence and hazardous effects of chronic viral infection heighten the need to develop novel methodologies for the detection and treatment of this infection. Bacteriophages, viruses that specifically infect bacterial cells, with a long-established tradition in molecular biology and biotechnology have recently been introduced as novel tools for the prevention, diagnosis and treatment of HBV infection. Bacteriophages, due to tremendous genetic flexibility, represent potential to undergo a huge variety of surface modifications. This property has been the rationale behind introduction of phage display concept. This powerful approach, together with combinatorial chemistry, has shaped the concept of phage display libraries with diverse applications for the detection and therapy of HBV infection. This review aims to offer an insightful overview of the potential of bacteriophages in the development of helpful prophylactic (vaccine design), diagnostic and therapeutic strategies for HBV infection thereby providing new perspectives to the growing field of bacteriophage researches directing towards HBV infection.

Indexed as

Cell Surface Display TechniquesDrug DesignAnimalsAntiviral AgentsBacteriophagesGene Expression Regulation, ViralGenotypeHepatitis BHepatitis B VaccinesHepatitis B virusHumansMolecular Targeted TherapyPredictive Value of TestsAntiviral AgentsHepatitis B VaccinesBacteriophageBiopanningDiagnosisHepatitis B virusPhage displayPhage libraryTreatmentVaccine development

Identifiers

PMID25206272
PMCPMC4155358
OpenAlexW2065203664

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.