ReviewWorld journal of gastroenterology2014
Chronic hepatitis B in 2014: great therapeutic progress, large diagnostic deficit.
Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Influence of AFP on surgical outcomes in non-B non-C patients with curative resection for hepatocellular carcinoma.Clinical and experimental medicine · 2023Article
- Diagnosis experiences from 50 hepatitis B patients in Chongqing, China: a qualitative study.BMC public health · 2021Article
- Progress and challenges in the comprehensive management of chronic viral hepatitis: Key ways to achieve the elimination.World journal of gastroenterology · 2021Review
- The impact of testing and treatment on the dynamics of Hepatitis B virus.F1000Research · 2021Article
- Designing an electronic blood-borne virus risk alert to improve uptake of testing.International journal of STD & AIDS · 2020Article
- Experiences of Screening for Human Immunodeficiency Virus, Viral Hepatitis B, and Viral Hepatitis C Infections at a Hospital in Thailand: Test Utilization and Outcomes.Medical science monitor basic research · 2019Article
- Self-motivated medical care-seeking behaviors and disease progression in a community-based cohort of chronic hepatitis B virus-infected patients in China.BMC public health · 2019Article
- Prevalence of Hepatitis B, Hepatitis C, and HIV in Multiply Transfused Sickle Cell Disease Patients from Oman.Mediterranean journal of hematology and infectious diseases · 2019Article
- CRISPR/Cas9: the Jedi against the dark empire of diseases.Journal of biomedical science · 2018Review
- Serum lipids as an indicator for the alteration of liver function in patients with hepatitis B.Lipids in health and disease · 2018Article
- Estimating the scale of chronic hepatitis B virus infection among migrants in EU/EEA countries.BMC infectious diseases · 2018Article
- Risk factors for hepatitis B transmission in South Brazil.Memorias do Instituto Oswaldo Cruz · 2017Article
- Article
- In vitro model of production of antibodies; a new approach to reveal the presence of key bacteria in polymicrobial environments.BMC microbiology · 2016Article
- Different Variants in Reverse Transcriptase Domain Determined by Ultra-deep Sequencing in Treatment-naïve and Treated Indonesian Patients Infected with Hepatitis B Virus.The Kobe journal of medical sciences · 2016Article
- Low hepatitis B testing among migrants: a cross-sectional study in a UK city.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016Article
- A conserved RNA structural element within the hepatitis B virus post-transcriptional regulatory element enhance nuclear export of intronless transcripts and repress the splicing mechanism.Molecular biology reports · 2015Article
- Early-life exposures to infectious agents and later cancer development.Cancer medicine · 2015Review
- Novel insights into the function and dynamics of extracellular matrix in liver fibrosis.American journal of physiology. Gastrointestinal and liver physiology · 2015Review
- HBV epidemiology and genetic diversity in an area of high prevalence of hepatitis B in southern Brazil.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review analyzes progress and limitations of diagnosis, screening, and therapy of patients with chronic hepatitis B infection. A literature review was carried out by framing the study questions. Vaccination in early childhood has been introduced in most countries and reduces the infection rate. Treatment of chronic hepatitis B can control viral replication in most patients today. It reduces risks for progression and may reverse liver fibrosis. The treatment effect on development of hepatocellular carcinoma is less pronounced when cirrhosis is already present. Despite the success of vaccination and therapy chronic hepatitis B remains a problem since many infected patients do not know of their disease. Although all guidelines recommend screening in high risk groups such as migrants, these suggestions have not been implemented. In addition, the performance of hepatocellular cancer surveillance under real-life conditions is poor. The majority of people with chronic hepatitis B live in resource-constrained settings where effective drugs are not available. Despite the success of vaccination and therapy chronic hepatitis B infection remains a major problem since many patients do not know of their disease. The problems in diagnosis and screening may be overcome by raising awareness, promoting partnerships, and mobilizing resources.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.