Evidence map›Paper›PMID 25205661›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2015

Fusion and Fission of Cognitive Functions in the Human Parietal Cortex.

Gina F Humphreys, Matthew A Lambon Ralph

Abstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Trial
  8. Resolving the Abstract-Concrete Paradox in the Angular Gyrus: A Multimethod Investigation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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  13. Lesion-symptom mapping reveals differential relationships between language and precise versus approximate numeracy.Cortex; a journal devoted to the study of the nervous system and behavior · 2025
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78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gina F HumphreysNeuroscience and Aphasia Research Unit (NARU), School of Psychological Sciences, University of Manchester, Brunswick St., Manchester M13 9PL, UK.
Matthew A Lambon RalphNeuroscience and Aphasia Research Unit (NARU), School of Psychological Sciences, University of Manchester, Brunswick St., Manchester M13 9PL, UK.

Funding

Medical Research Council MR/J004146/1
6 · The paper itself

Abstract

How is higher cognitive function organized in the human parietal cortex? A century of neuropsychology and 30 years of functional neuroimaging has implicated the parietal lobe in many different verbal and nonverbal cognitive domains. There is little clarity, however, on how these functions are organized, that is, where do these functions coalesce (implying a shared, underpinning neurocomputation) and where do they divide (indicating different underlying neural functions). Until now, there has been no multi-domain synthesis in order to reveal where there is fusion or fission of functions in the parietal cortex. This aim was achieved through a large-scale activation likelihood estimation (ALE) analysis of 386 studies (3952 activation peaks) covering 8 cognitive domains. A tripartite, domain-general neuroanatomical division and 5 principles of cognitive organization were established, and these are discussed with respect to a unified theory of parietal functional organization.

Indexed as

Models, NeurologicalCognitionHumansLikelihood FunctionsParietal Lobeactivation likelihood estimation analysisangular gyrusattentionepisodic retrievalfunctional neuroimaginginferior parietal lobuleintra-parietal sulcusneuropsychologynumerical tasksparietal cortexphonological processingsemantic processingsentence-level processingsupramarginal gyrusthe default-mode networktool-related tasks

Identifiers

PMID25205661
PMCPMC4585503

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.