ArticleEuropean journal of clinical nutrition2015
Inflammation profile in overweight/obese adolescents in Europe: an analysis in relation to iron status.
Article in European journal of clinical nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Overnutrition is a risk factor for iron, but not for zinc or vitamin A deficiency in children and young people: a systematic review and meta-analysis.BMJ global health · 2024Pooled it
- Adjusting ferritin concentrations for inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project.The American journal of clinical nutrition · 2017Pooled it
- Concurrent and aerobic exercise training promote similar benefits in body composition and metabolic profiles in obese adolescents.Lipids in health and disease · 2015Trial
- Inflammation Does Not Mediate Relationships between BMI/BMI-for-AgeCurrent developments in nutrition · 2026Article
- The Association Between SerumInternational journal of endocrinology · 2026Article
- The Interplay Between Iron Metabolism and Insulin Resistance: A Key Factor in Optimizing Obesity Management in Children and Adolescents.Nutrients · 2025Review
- The association between fat distribution and α1-acid glycoprotein levels among adult females in the United States.Lipids in health and disease · 2024Observational
- The Impact of Paediatric Obesity on Drug Pharmacokinetics: A Virtual Clinical Trials Case Study with Amlodipine.Pharmaceutics · 2024Article
- Cohort-Based Reference Values for Serum Ferritin and Transferrin and Longitudinal Determinants of Iron Status in European Children Aged 3-15 Years.The Journal of nutrition · 2024Article
- Human Nutrition Research in the Data Era: Results of 11 Reports on the Effects of a Multiple-Micronutrient-Intervention Study.Nutrients · 2024Review
- Review
- Roux-en-Y Gastric Bypass as a Treatment for Hepatic Iron Overload: An Exploratory Study.Obesity surgery · 2022Article
- Novel insights into the consequences of obesity: a phenotype-wide Mendelian randomization study.European journal of human genetics : EJHG · 2022Article
- Association Between Childhood Body Size and Premenstrual Disorders in Young Adulthood.JAMA network open · 2022Article
- Anthropometric Markers and Iron Status of 6-12-Year-Old Thai Children: Associations and Predictors.Journal of nutrition and metabolism · 2021Article
- Serum Calprotectin and Chemerin Concentrations as Markers of Low-Grade Inflammation in Prepubertal Children with Obesity.International journal of environmental research and public health · 2020Article
- Prevalence of iron deficiency and related factors in Spanish adolescents.European journal of pediatrics · 2020Article
- Diet as moderator in the association of adiposity with inflammatory biomarkers among adolescents in the HELENA study.European journal of nutrition · 2019Article
- Effects of Pubertal Status and Inflammation on the Use of Ferritin to Define Iron Deficiency in Children With Overweight or Obesity.Nutrition and metabolic insights · 2019Article
- Prevalence of Anaemia and Iron Deficiency among Primary Schoolchildren in Malaysia.International journal of environmental research and public health · 2018Article
Corrections and comments
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Authors and funding
19 authors at 15 institutions in 10 countries.
Funding
Abstract
BACKGROUND/
objectivesThe objectives of this study were to investigate the relationship between inflammatory parameters (CRP, c-reactive protein; AGP, α1-acid glycoprotein), iron status indicators (SF, serum ferritin; sTfR, soluble transferrin receptor) and body mass index (BMI) z-score, fat-free mass (FFM) and fat mass (FM) in European adolescents. Differences in intake for some nutrients (total iron, haem and non-haem iron, vitamin C, calcium, proteins) were assessed according to BMI categories, and the association of nutrient intakes with BMI z-score, FM and FFM was evaluated.
methodsA total of 876 adolescents participating in the Healthy Lifestyle in Europe by Nutrition in Adolescence-Cross Sectional Study were included in the study sample.
resultsMean CRP values (standard error; s.e.) were significantly higher in overweight/obese adolescents (1.7±0.3 and 1.4±0.3 mg/l in boys and girls, respectively) than in thin/normal-weight adolescents (1.1±0.2 and 1.0±0.1 mg/l in boys and girls, respectively) (P<0.05). For boys, mean SF values (s.e.) were significantly higher in overweight/obese adolescents (46.9±2.7 μg/l) than in thin/normal-weight adolescents (35.7±1.7 μg/l) (P<0.001), whereas median sTfR values did not differ among BMI categories for both boys and girls. Multilevel regression analyses showed that BMI z-score and FM were significantly related to CRP and AGP (P<0.05). Dietary variables did not differ significantly among BMI categories, except for the intake of vegetable proteins, which, for boys, was higher in thin/normal-weight adolescents than in overweight/obese adolescents (P<0.05).
conclusionsThe adiposity of the European adolescents was sufficient to cause chronic inflammation but not sufficient to impair iron status and cause iron deficiency.
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