ArticlePlanta2014
Identification of microRNAs and their targets in tomato infected with Cucumber mosaic virus based on deep sequencing.
Article in Planta, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Decoding MicroRNA-Guided Antiviral Defense in Cucurbitaceae: Regulatory Networks, RNA Silencing Cross-Talk, and Emerging Strategies for Crop Resilience.International journal of molecular sciences · 2026Review
- Evolutionarily New Solanaceous DCL2 Family Members Acquire Functions in Tomato.Molecular plant pathology · 2025Article
- Elucidating long non-coding RNA networks in tomato plants in response to Funneliformis mosseae colonization and cucumber mosaic virus infection.BMC plant biology · 2025Article
- Analysis of Genetic Diversity in Adzuki Beans (Plants (Basel, Switzerland) · 2023Article
- Comprehensive regulatory networks for tomato organ development based on the genome and RNAome of MicroTom tomato.Horticulture research · 2023Article
- A Novel miRNA in Rice Associated with the Low Seed Setting Rate Symptom of Rice Stripe Virus.International journal of molecular sciences · 2023Article
- The roles of microRNAs in horticultural plant disease resistance.Frontiers in genetics · 2023Review
- Multiple Functions of MiRNAs inLife (Basel, Switzerland) · 2022Review
- Transcriptional and post-transcriptional regulation of RNAi-related gene expression during plant-virus interactions.Stress biology · 2022Review
- Molecular mechanism of modulating miR482b level in tomato with botrytis cinerea infection.BMC plant biology · 2021Article
- Whole-Genome Doubling Affects Pre-miRNA Expression in Plants.Plants (Basel, Switzerland) · 2021Article
- Integrated Analysis of microRNA and mRNA Transcriptome Reveals the Molecular Mechanism ofFrontiers in microbiology · 2021Article
- Suppression of nbe-miR1919c-5p Expression inViruses · 2020Article
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- Identification of microRNAs regulated by tobacco curly shoot virus co-infection with its betasatellite in Nicotiana benthamiana.Virology journal · 2019Article
- Comparative transcriptome analysis shows the defense response networks regulated by miR482b.Plant cell reports · 2019Article
- Tomato lncRNA23468 functions as a competing endogenous RNA to modulateHorticulture research · 2019Article
- Suppression of nbe-miR166h-p5 attenuates leaf yellowing symptoms of potato virus X on Nicotiana benthamiana and reduces virus accumulation.Molecular plant pathology · 2018Article
- New insights into tomato microRNAs.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) play important regulatory roles in plant development and stress responses. Tomato is an economically important vegetable crop in the world with publicly available genomic information database, but only a limited number of tomato miRNAs have been identified. In this study, two independent small RNA libraries from mock and Cucumber mosaic virus (CMV)-infected tomatoes were constructed, respectively, and sequenced with a high-throughput Illumina Solexa system. Based on sequence analysis and hairpin structure prediction, a total of 50 plant miRNAs and 273 potentially candidate miRNAs (PC-miRNAs) were firstly identified in tomato, with 12 plant miRNAs and 82 PC-miRNAs supported by both the 3p and 5p strands. Comparative analysis revealed that 79 miRNAs (including 15 new tomato miRNAs) and 40 PC-miRNAs were differentially expressed between the two libraries, and the expression patterns of some new tomato miRNAs and PC-miRNAs were further validated by qRT-PCR. Moreover, potential targets for some of the known and new tomato miRNAs were identified by the recently developed degradome sequencing approach, and target annotation indicated that they were involved in multiple biological processes, including transcriptional regulation and virus resistance. Gene ontology analysis of these target transcripts demonstrated that defense response- and photosynthesis-related genes were most affected in CMV-Fny-infected tomatoes. Because tomato is not only an important crop but also is a genetic model for basic biology research, our study contributes to the understanding of miRNAs in response to virus infection.
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