Evidence map›Paper›PMID 25203673›Full record

ReviewMolecular endocrinology (Baltimore, Md.)2014

Minireview: Steroid/nuclear receptor-regulated dynamics of occluding and anchoring junctions.

Gary L Firestone, Bhumika J Kapadia

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecular endocrinology (Baltimore, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gary L FirestoneDepartment of Molecular and Cell Biology and The Cancer Research Laboratory, University of California at Berkeley, Berkeley, California 94720-3200.
Bhumika J Kapadia
University of California, Berkeley · US

Funding

STEROID CONTROL OF EPITHELIAL CELL-CELL INTERACTIONSR01DK042799 · NIDDK · UNIVERSITY OF CALIFORNIA BERKELEY · PI FIRESTONE, GARY L · 1990 to 2011
$2.2M
Steroid control of epithelial cell-cell interactionsR56DK042799 · NIDDK · UNIVERSITY OF CALIFORNIA BERKELEY · PI FIRESTONE, GARY L · 2005 to 2007
$370k
NIDDK NIH HHS DK-42799NIDDK NIH HHS R01 DK042799NIDDK NIH HHS R56 DK042799
6 · The paper itself

Abstract

A diverse set of physiological signals control intercellular interactions by regulating the structure and function of occluding junctions (tight junctions) and anchoring junctions (adherens junctions and desmosomes). These plasma membrane junctions are comprised of multiprotein complexes of transmembrane and cytoplasmic peripheral plasma membrane proteins. Evidence from many hormone-responsive tissues has shown that expression, modification, molecular interactions, stability, and localization of junctional complex-associated proteins can be targeted by nuclear hormone receptors and their ligands through transcriptional and nontranscriptional mechanisms. The focus of this minireview is to discuss molecular, cellular, and physiological studies that directly link nuclear receptor- and ligand-triggered signaling pathways to the regulation of occluding and anchoring junction dynamics.

Indexed as

Adherens JunctionsAnimalsCell MembraneHumansLigandsReceptors, Cytoplasmic and NuclearReceptors, SteroidSignal TransductionTight JunctionsLigandsReceptors, Cytoplasmic and NuclearReceptors, Steroid

Identifiers

PMID25203673
PMCPMC4213367
OpenAlexW2017046987

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.