ArticleAddiction (Abingdon, England)2015
Ongoing impact of HIV infection on mortality among people who inject drugs despite free antiretroviral therapy.
Article in Addiction (Abingdon, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04790201 (Adaptation of the Friendship Bench Counseling Intervention to Improve Mental Health and HIV Care Engagement Outcomes Among People Living With HIV Who Inject Drugs in Vietnam), which is not on this map. Cited by 15 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Adaptation of the Friendship Bench Counseling Intervention to Improve Mental Health and HIV Care Engagement Outcomes Among People Living With HIV Who Inject Drugs in Vietnam
Who cites it
15 citing papers in PubMed.
- Trial
- Causes and risk factors of death among people who inject drugs in Indonesia, Ukraine and Vietnam: findings from HPTN 074 randomized trial.BMC infectious diseases · 2023Trial
- All-cause mortality and overdose deaths among 4192 people who inject drugs in Stockholm: a 10-year register-based cohort study.Harm reduction journal · 2026Article
- Mortality among HIV-Positive and HIV-Negative People Who Inject Drugs in Mizoram, Northeast India: A Repeated Cross-Sectional Study (2007-2021).International journal of environmental research and public health · 2024Article
- Mortality among people who inject drugs - the interwoven roles of fentanyl and HIV: a community-based cohort study.European journal of public health · 2024Article
- Acceptability and feasibility of long-acting injectable antiretroviral therapy for HIV-infected persons who inject drugs in Vietnam: A qualitative study.The Lancet regional health. Western Pacific · 2023Article
- A cohort study revealed high mortality among people who inject drugs in Hai Phong, Vietnam.Journal of clinical epidemiology · 2021Article
- Article
- Review
- Depressive Symptoms at HIV Testing and Two-Year All-Cause Mortality Among Men Who Inject Drugs in Vietnam.AIDS and behavior · 2019Article
- Mortality and virological failure among HIV-infected people who inject drugs on antiretroviral treatment in China: An observational cohort study.Drug and alcohol dependence · 2017Observational
- Predictors of Mortality within Prison and after Release among Persons Living with HIV in Indonesia.Research and reports in tropical medicine · 2017Article
- Reducing rates of preventable HIV/AIDS-associated mortality among people living with HIV who inject drugs.Current opinion in HIV and AIDS · 2016Review
- Sex-Based Differences in Rates, Causes, and Predictors of Death Among Injection Drug Users in Vancouver, Canada.American journal of epidemiology · 2016Article
- Impact of binge alcohol on mortality among people who inject drugs.Addictive behaviors reports · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
aimsTo determine the impact of HIV infection on mortality over time among people who inject drugs (PWID) in settings with free HIV/AIDS care. DESIGN AND
settingProspective cohort study of PWID in Vancouver, Canada, recruited between May 1996 and December 2011. We ascertained morality rates and causes of death through a confidential linkage with the provincial vital statistics registry.
participantsA total of 2283 individuals were followed for a median of 60.9 months (interquartile range: 34.4-113.1), among whom 622 (27.2%) individuals were HIV-positive at baseline, and 179 (7.8%) seroconverted during follow-up. MEASUREMENTS: The primary and secondary outcomes of interests were all-cause mortality and cause of death, respectively. The main independent variable of interest was HIV serostatus (positive versus negative). We used Cox proportional hazards regression to determine factors associated with mortality, including socio-demographic variables, drug use behaviors and other risk behaviors.
findingsDuring the study period, 491 (21.5%) individuals died. In multivariate analyses, HIV infection remained associated independently with all-cause mortality (adjusted hazard ratio = 3.15; 95% CI: 2.59-3.82). While all-cause mortality rates declined markedly during the study period (P < 0.001), the independent effect of HIV infection on mortality remained unchanged over time (P = 0.640). Among HIV-positive individuals, significant changes in causes of death from infectious and AIDS-related causes to non-AIDS-related etiologies were observed.
conclusionsHIV infection continues to have a persistent impact on mortality rates among people who inject drugs in settings with free HIV/AIDS care, although causes of death have shifted markedly from infectious and AIDS-related causes to non-AIDS-related etiologies.
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