Evidence map›Paper›PMID 25203204›Full record

ArticleDevelopmental cell2014

Flipping a phosphate switch on kinesin-II to turn IFT around.

Branch Craige, George B Witman

Abstract readComment
In one paragraph

Article in Developmental cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Appearing and disappearing acts of cilia.Journal of biosciences · 2023
    Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Branch CraigeDepartment of Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
George B WitmanDepartment of Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA. Electronic address: george.witman@umassmed.edu.

Funding

Flagellar Motility and AssemlbyR37GM030626 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI WITMAN, GEORGE B · 2007 to 2016
$6.3M
CELL AND MOLECULAR BIOLOGY OF REPRODUCTIONT32HD007439 · NICHD · WORCESTER FOUNDATION FOR BIOMEDICAL RES · PI WITMAN, GEORGE B · 1993 to 2015
$1.3M
NICHD NIH HHS T32 HD007439NIGMS NIH HHS R37 GM030626
6 · The paper itself

Abstract

Cilia and flagella are assembled and maintained by the motor-driven, bidirectional traffic of large protein complexes in a process termed intraflagellar transport (IFT). In this issue of Developmental Cell, Liang et al. (2014) report that IFT is regulated in part by the phosphorylation status of the kinesin-II subunit FLA8/KIF3B.

Indexed as

Gene Expression Regulation, PlantAnimalsCalcium-Binding ProteinsChlamydomonas reinhardtiiFlagellaKinesinsCalcium-Binding Proteinskinesin-IIKinesins

Identifiers

PMID25203204
PMCPMC4384660

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.