Evidence map›Paper›PMID 25202874›Full record

ArticleCurrent biology : CB2014

Centromere licensing: Mis18 is required to Polo-ver.

Meghan C Barnhart-Dailey, Daniel R Foltz

Open access · bronzeAbstract readComment
In one paragraph

Article in Current biology : CB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Meghan C Barnhart-DaileyDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22901, USA.
Daniel R FoltzDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22901, USA; Department of Cell Biology, University of Virginia, Charlottesville, VA 22901, USA. Electronic address: drf3q@virginia.edu.
University of Virginia · US

Funding

TRAINING IN CELL AND MOLECULAR BIOLOGYT32GM008136 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI STUKENBERG, P. TODD · 1985 to 2020
$8.5M
Assembly and epigenetic inheritance of the human centromereR01GM111907 · NIGMS · UNIVERSITY OF VIRGINIA · PI FOLTZ, DANIEL RICHARD · 2014 to 2022
$2.8M
The role of CENP-A in mammalian centromere specificationF32GM067401 · NIGMS · LUDWIG INSTITUTE FOR CANCER RESEARCH · PI FOLTZ, DANIEL RICHARD · 2003 to 2005
$139k
NIGMS NIH HHS F32 GM067401NIGMS NIH HHS R01 GM111907NIGMS NIH HHS T32 GM008136
6 · The paper itself

Abstract

The Mis18 complex is a critical player in determining when and where centromeres are built. A new study identifies Polo-like kinase (Plk1) as a positive regulator required for the localization of Mis18 to centromeres. This is a critical step that is essential for proper centromere function and maintaining the integrity of the genome.

Indexed as

AutoantigensCell Cycle ProteinsCentromereChromosomal Proteins, Non-HistoneHumansProtein Serine-Threonine KinasesProto-Oncogene ProteinsAutoantigensCell Cycle ProteinsChromosomal Proteins, Non-HistoneProtein Serine-Threonine KinasesProto-Oncogene Proteins

Identifiers

PMID25202874
PMCPMC5881566
OpenAlexW2025956880

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.