ArticleBioMed research international2014
Systematic analysis of the association between gut flora and obesity through high-throughput sequencing and bioinformatics approaches.
Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
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Who cites it
60 citing papers in PubMed, 110 citations in OpenAlex.
- Trial
- Effects of Synbiotic Supplement on Human Gut Microbiota, Body Composition and Weight Loss in Obesity.Nutrients · 2020Trial
- Synergic effect of diet and polysaccharide-based complex administration in the treatment of children and adolescents with metabolically unhealthy obesity: the Polymets Study.Journal of endocrinological investigation · 2026Article
- Transformer Models, Graph Networks, and Generative AI in Gut Microbiome Research: A Narrative Review.Bioengineering (Basel, Switzerland) · 2026Review
- Secondary open structural rhinoplasty with costal cartilage grafts.Maxillofacial plastic and reconstructive surgery · 2025Article
- Mediation effect and metabolic pathways of gut microbiota in the associations between lifestyles and dyslipidemia.NPJ biofilms and microbiomes · 2025Article
- Analyzing microbiome data with taxonomic misclassification using a zero-inflated Dirichlet-multinomial model.BMC bioinformatics · 2025Article
- Gut microbiota signatures across BMI categories in adults and combined diagnostic value with clinical indicators for early obesity risk stratification.Frontiers in microbiology · 2025Article
- Gut Microbiota Regulates the Homeostasis of Dendritic Epidermal T Cells.Life (Basel, Switzerland) · 2024Article
- Characteristics of gut microbiota and serum metabolism in patients with atopic dermatitis.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Effects of fermented sweet potato residue on nutrient digestibility, meat quality, and intestinal microbes in broilers.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Article
- A cross-sectional study on gut microbiota in patients with chronic kidney disease undergoing kidney transplant or hemodialysis.American journal of translational research · 2023Article
- Therapeutic efficacy of liraglutide versus metformin in modulating the gut microbiota for treating type 2 diabetes mellitus complicated with nonalcoholic fatty liver disease.Frontiers in microbiology · 2023Article
- Article
- Deep neural networks with knockoff features identify nonlinear causal relations and estimate effect sizes in complex biological systems.GigaScience · 2022Article
- Simulated Digestion and Fermentation In Vitro by Obese Human Gut Microbiota of Sulforaphane from Broccoli Seeds.Foods (Basel, Switzerland) · 2022Article
- How is gut microbiome of patients with familial adenomatous polyposis different from healthy people?Medicine · 2022Article
- Characterization of the gut microbiota in hemodialysis patients with sarcopenia.International urology and nephrology · 2022Article
- A Possible Link between Gut Microbiome Composition and Cardiovascular Comorbidities in Psoriatic Patients.Journal of personalized medicine · 2022Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eighty-one stool samples from Taiwanese were collected for analysis of the association between the gut flora and obesity. The supervised analysis showed that the most, abundant genera of bacteria in normal samples (from people with a body mass index (BMI) ≤ 24) were Bacteroides (27.7%), Prevotella (19.4%), Escherichia (12%), Phascolarctobacterium (3.9%), and Eubacterium (3.5%). The most abundant genera of bacteria in case samples (with a BMI ≥ 27) were Bacteroides (29%), Prevotella (21%), Escherichia (7.4%), Megamonas (5.1%), and Phascolarctobacterium (3.8%). A principal coordinate analysis (PCoA) demonstrated that normal samples were clustered more compactly than case samples. An unsupervised analysis demonstrated that bacterial communities in the gut were clustered into two main groups: N-like and OB-like groups. Remarkably, most normal samples (78%) were clustered in the N-like group, and most case samples (81%) were clustered in the OB-like group (Fisher's P value = 1.61E - 07). The results showed that bacterial communities in the gut were highly associated with obesity. This is the first study in Taiwan to investigate the association between human gut flora and obesity, and the results provide new insights into the correlation of bacteria with the rising trend in obesity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.